Study On The Distribution Of TCM Syndrome Types Of Type 2 Diabetes Complicated With Urinary Tract Infection Based On Cluster Analysis

Objective: The general data of 200 patients with Type 2 diabetes mellitus combined with Urinary tract infection and the four diagnosis data of traditional Chinese medicine were statistically analyzed,and the TCM symptom type and distribution of T2 DM combined with UTI were systematically discussed,the distribution of its main symptom type was established,and the distribution of each symptom type in related data was studied.It provides a reference for better guidance on TCM differentiation and treatment of patients with T2 DM and UTI in the future.Methods: From January 2022 to December 2022,200 patients with T2 DM combined UTI diagnosis were collected from the outpatient and inpatient departments of Ruikang Hospital Affiliated to Guangxi University of Chinese Medicine.The TCM symptom data will be collected by cluster analysis method to summarize and classify TCM symptoms,and divide them into primary and secondary symptoms according to the frequency of symptoms,and the 200 patients will be grouped according to TCM classification,and the distribution law of TCM symptom type will be studied,and the personal data and test data of each group of patients will be statistically analyzed,and the connection between TCM symptom type and each data will be studied.Results: 1.The general data of 200 patients were analyzed,among which women,patients with body mass index(BMI)were normal and overweight,oral drugs to control blood sugar,had a history of smoking,had a history of drinking,and had previously diagnosed hypertension.2.According to the cluster analysis of the collected TCM symptom data,the clustering center was set to 24.5,and the symptoms were summarized and divided into kidney yang deficiency evidence,qi and yin deficiency evidence,and humidity and heat mutual evidence according to their symptom characteristics.3.The distribution of the three TCM certificate types was qi and yin deficiency evidence(60.0%)> humid heat mutual evidence(26.5%)> kidney yang deficiency deficiency certificate(13.5%).There were differences in age,smoking history,disease course,fasting blood glucose,blood glucose 2hours after meals,and urea nitrogen(all P < 0.05).The two false certificates of humid heat and qiyin accounted for the largest proportion of the disease course < 10 years and the ≥ 10 years of the disease,respectively,and the difference was statistically significant(P<0.01);the patients with a history of smoking had the most moist heat mutual evidence(P<0.05);among the test results,patients with high fasting blood glucose,2-hour postprandial blood glucose and glycated hemoglobin had more evidence of renal yang deficiency,and the difference was statistically significant(P=0.026<0.05),and the difference was statistically significant in the patients with high urea nitrogen(P=0.018<0.05).4.A total of 124 pathogenic bacteria were isolated from urine samples of 200 patients with T2 DM and UTI,including 99 strains of gram-negative bacteria(accounting for 79.9%,mainly Escherichia coli,Klebsiella pneumoniae and Proteobacter mirabili),19 strains of gram-positive bacteria(accounting for 15.3%,mainly enterococcus,Streptococcus agalactis and staphylococcus superficial),and 4 fungi(accounting for 3.2%).There was no significant difference in the distribution of different TCM symptom types in Escherichia coli(P=0.154>0.05).76 pathogenic strains of Escherichia coli were isolated for statistical analysis,among which the sensitivity rates to amikacin,ertapenem,meropenem,cefotetan and imipenem were 100%,followed by piperacillin/tazobactam,cefoperazone/sulbactam and other sensitivity rates were higher than 90%.Among the 76 pathogenic strains,the resistance rate of ciprofloxacin,ampicillin and levofloxacin was higher than50%,followed by the resistance rate of compound trimoxazole,ampicillin/sulbactam and cefazoline was higher than 30%.Conclusions: 1.Set the clustering center to 24.5,and divide the types into qi-yin deficiency,humid-heat mutual bonding,and renal yang deficiency according to the syndrome,and the incidence rate is qiyin deficiency evidence > humid heat mutual bonding > renal yang deficiency deficiency evidence.2.There is a correlation between TCM certificate type and disease course,smoking history and number of complications.3.There is a correlation between TCM certificate type and fasting blood glucose,blood glucose 2 hours after meals,glycated hemoglobin,and urea nitrogen.4.There is no significant difference in the probability of infection with Escherichia coli in traditional Chinese medicine.