| Background: Essential hypertension(EH)is a common chronic non-communicable disease that has become an important public health challenge worldwide.Research has confirmed that unhealthy dietary and behavioral habits can significantly increase the risk of EH.At present,great progress has been made in the pharmacological treatment of EH,but it remains an important cause of CVD occurrence and death worldwide.Numerous evidence suggests that developing good exercise habits and changing sedentary or lowactivity states have become effective methods for preventing and assisting in the treatment of EH.Due to poor adherence to long-term exercise behavior adjustment,how to provide effective blood pressure intervention,health counseling,and induce sustainable behavior change in EH patients are increasingly attracting attention.Objective: Through the intelligent Hypertension Excellence Center(iHEC)platform,exercise intervention is carried out on sedentary and low-activity EH patients to evaluate the effectiveness of digital medical tools in managing EH.Methods: 46 EH patients who underwent physical examination at the Health Management/Physical Examination Center of Sichuan Provincial People’s Hospital from July to November 2022 were selected.All EH patients were randomly divided into control group,intensive intervention group and intervention group by random number method.The intensive intervention group was given a large amount of activity(daily step count >12500 steps)intervention,the intervention group was given a general amount of activity(7500 steps < daily step count ≤ 12500 steps)intervention,while the blank control group was not given exercise intervention and only received HTN health education at enrollment.After 12 weeks of intervention,changes in home self-measured blood pressure,dynamic blood pressure,weight,waist circumference,body mass index(BMI),step index,biochemical metabolism-related indicators,body composition and visceral fat were analyzed and compared among the three groups of EH patients.Results: A total of 42 EH patients completed the trial,including 13 in the intensive intervention group,16 in the conventional intervention group and 13 in the control group.Compared with before intervention,systolic blood pressure(SBP),home self-measured blood pressure and dynamic blood pressure were significantly reduced after intensive intervention(all P <0.05),among which clinic SBP decreased by 7.69±7.34 mm Hg,home self-measured SBP decreased by 7.68±5.90 mm Hg and home self-measured diastolic blood pressure(DBP)decreased by 6.97±4.31 mm Hg;while in dynamic blood pressure: average SBP for all day decreased by 10.00±9.49 mm Hg and DBP decreased by6.85±4.62 mm Hg;average SBP during daytime decreased by 11.00(5)mm Hg and DBP decreased by 6.85±4.36 mm Hg;average SBP at night decreased by 5.58±7.57 mm Hg and DBP decreased by 5.00±5.57 mm Hg.At the same time,there were significant differences between pre-and post-intervention weight,waist circumference,BMI,step index,blood uric acid,low-density lipoprotein(LDL),high-density lipoprotein(HDL),body fat rate,subcutaneous fat area and average heart rate for 24h(all P <0.05).In addition to this comparison with conventional intervention group showed that LDL-C,home selfmeasured DBP,average daytime and nighttime DBPs as well as average nighttime heart rate were significantly reduced in intensive intervention group with statistically significant differences(all P <0.05).Conclusion: By adopting the iHEC platform management and increasing the amount of daily activity through intensified exercise intervention,it can significantly reduce the clinic blood pressure,home self-test blood pressure,dynamic blood pressure and heart rate of EH patients,significantly reduce obesity,effectively reduce blood uric acid and blood lipid levels and significantly improve fat distribution. |
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