| Objective:To observe the clinical efficacy of stimulating the Hua Tuo Jia Ji point through thunder-fire moxibustion for the treatment of ankylosing spondylitis associated with renal deficiency and Du meridian cold syndrome.Methods:90 patients who met diagnostic criteria for ankylosing spondylitis and with renal deficiency and Du meridian cold syndrome were randomly assigned to thunder-fire moxibustion group(thunder-fire moxibustion normalized treatment +basic pharmacotherapy group),moxa-moxibustion group(ordinary moxa-moxibustion + basic pharmacotherapy group)and pharmacotherapy group(basic pharmacotherapy group),30 cases each group.All these three groups were compared in terms of spinal column activities(finger-floor distance(FFD),occiput-wall distance(OWD))before and after treatments,Bath ankylosing spondylitis disease activity index(BASDAI),Bath ankylosing spondylitis functional index(BASFI),inflammatory indexes(erythrocyte sedimentation rate(ESR),C-Reactive protein(CRP)),visual analogue scale(VAS),efficacy difference on TCM syndrome score and the overall efficacy evaluation of these three groups.Results:1.The total effective rate of the thunder-fire moxibustion group,25 cases were markedly effective,14 cases were effective and 1 case was no effective,the total effective rate being 97%;for the moxa-moxibustion group,16 cases were markedly effective,7 cases were effective and 7 cases were no effective,the total effective rate being 77%;for the pharmacotherapy group,4 cases were markedly effective,12 cases were effective and 14 cases were no effective,the total effective rate being 53%;for the difference among these three groups(P<0.01).2.In the difference on spinal column activities,the efficacy of thunder-fire moxibustion treatment group was superior to those of the other two groups(P<0.05)whereas there was no significant difference between the moxa-moxibustion group and the pharmacotherapy group(P>0.05).3.Difference on BASDAI among these three groups after treatments;the thunder-fire moxibustion group and the moxa-moxibustion group were more effective than the pure pharmacotherapy group(P<0.05).4.Difference on BASFI among these three groups after treatments;the thunder-fire moxibustion group were more effective than the pharmacotherapy group(P<0.05).The moxa-moxibustion group began to take effect at D10after treatments(P<0.05).5.Difference on inflammatory factors among these three groups after treatments;the thunder-fire moxibustion group was more effective than the pure pharmacotherapy group(P<0.05).At D15 after treatments,the moxa-moxibustion group and pharmacotherapy group started to present significant difference(P<0.05).6.Difference on pain score(VAS)among these three groups after treatments;the thunder-fire moxibustion group was more effective than the moxa-moxibustion group and the pure pharmacotherapy group(P<0.05).At D10 after treatments,the moxa-moxibustion group was significantly more effective than the pharmacotherapy group(P<0.05).7.Difference on TCM syndrome score among these three groups after treatments;the thunder-fire moxibustion group was more effective than the moxa-moxibustion group and the pure pharmacotherapy group(P<0.05).At D10,the moxa-moxibustion group was significantly more effective than the pharmacotherapy group(P<0.05).Conclusion:Upon comparison among these groups,as for simulating the Hua Tuo Jia Ji point for the treatment of ankylosing spondylitis associated with renal deficiency and Du meridian cold syndrome,the thunder-fire moxibustion had more significant efficacy and took effect more rapidly. |