Professor Liu Jianqiu’s Medication Rules For Combined Allergic Rhinitis And Asthma Syndrome Based On Data Mining

Objective:We used the traditional Chinese medicine inheritance support system(3.0)and data mining technology to analyze the core prescriptions and common drug pairs of Professor Liu Jianqiu in the treatment of allergic rhinitis-asthma syndrome,summarize the clinical experience of Professor Liu Jianqiu in the treatment of allergic rhinitis-asthma syndrome,and provide beneficial guidance for the treatment of allergic rhinitis-asthma syndrome based on syndrome differentiation.Methods:Original data collection:from November 2021 to January 2023,medical records of patients with allergic rhinitis and asthma syndrome who met the inclusion criteria in Professor Liu Jianqiu’s outpatient Department of the First Affiliated Hospital of Heilongjiang University of Chinese Medicine(gender,age,symptoms,information of four diagnoses,composition of prescriptions,etc.)were recorded into Excel.Data preprocessing:the original data of the first diagnosis of 17 8 patients were normalized and guided to the TCM inheritance assistance platform through Excel template.The basic information,symptoms,tongue and pulse,drugs and prescriptions of patients were statistically analyzed by frequency statistics,drug association rules and cluster analysis,and the clinical experience,medication rules and academic thoughts of Professor Liu Jianqiu in the treatment of allergic rhinitis and asthma syndrome were summarized.Results:1.A total of 178 patients were included in this study,including 128 female patients and 50 male patients,accounting for 71.91%and 28.09%respectively.Those affected are mainly aged 29 to 55.2.The main symptoms of CARAS include cough,dry cough,yellow sputum,white sputum,sneezing,nasal congestion,eye itching,ear itching,throat itching,serious spring,aggravated odor after irritation,constipation,upset and insomnia.Tongue quality to light red tongue,light white tongue mainly,tongue coating to less moss,thin white.The main pulse is the smooth pulse and the smooth solid pulse.3.The syndrome types of TCM are the most common syndrome of wind phlegm blocking lung,followed by phlegm-heat suppressing lung,cold drink suppressing lung,lung qi deficiency and lung kidney deficiency.4.The main therapeutic drugs were cicada slua,bitter almond,pinellia pinellia,licorice,Perilla leaf,burdock seed,schisandra,platycodon,ephedra root,ephedra,etc.;The efficacy of the drug is mainly to relieve surface,replenish deficiency,relieve cough and relieve asthma,and also to relieve astringency,clear heat,soothe liver and wind,regulate qi,etc.The four qi of medicine are mainly cold and warm,followed by flat,cool and hot;The five tastes are mainly ganxin,followed by bitter,sour and salty.The main channels are lung,heart,spleen and kidney.5.The core drug pairs were "Ephedra micra and ephedra root","cicada slua and Ephedra Micra Slua","cicada slua and Platy codon platy codon","Pinelli a pinellia,ephedra root and Ephedra Micra".6.The core prescriptions were as follows:1.Pinelli a pinellia,licorice,bitter almond,platy codon,Perilla leaf;Formula 2:Bitter Almond,cicada slough,Honey Aster,Coltsfoot Flower,Earth Dragon;Recipe 3:Licorice,bitter almond,Scutellaria scutellaria,cicada slough and cicada.Conclusions:1.Professor Liu Jianqiu identified the syndrome of wind phlegm blocking lung as the main syndrome type,followed by phlegm-heat stagnation lung syndrome,cold drink suppressing lung syndrome,lung qi deficiency syndrome and lung kidney deficiency syndrome.2.The frequent drugs used by Professor Liu Jianqiu to treat this disease were cicada slough,bitter almond,pinellia pinellia,licorice,Perilla leaves,burarctium,schisandra,platycodon,ephedra root and ephedra.The four qi of medicine are mainly cold and warm,followed by flat,cool and hot;The five tastes are mainly ganxin,followed by bitter,sour and salty.The main channels of drugs are lung,heart and spleen.Through drug association rule analysis and cluster analysis,there were 4 pairs of drug pairs and corner drugs,and 3 core prescriptions.3.Professor Liu believed that the initial link of the disease was lack of endowment,induced by external wind;Etiology and pathogenesis for the cardinal adverse sputum turbid obstructive lung;Treatment for lung and nose treatment,care for lung and kidney.