| Objective: Based on data mining method of dunhuang note in the horn of surgical disease compatibility and clinical application research,in order to provide modern clinical treatment of surgical disease scientific drug compatibility system and new treatment ideas,inheritance innovation of dunhuang TCM treatment of academic ideas,for dunhuang medical related literature excavation,sorting,research work provide certain reference.Methods: Through the 《Dunhuang Ancient Medical Prescription Research》,pick out the surgical disease of ancient medical medicine analysis,refer to relevant literature and data,depth combining the prescription and medicine,discuss corner medicine compatibility form,mechanism,law and application,combined with data mining method,explore drug characteristics and rules,summarizes the three medicine drug combination pattern and related rules,for the modern medical research and development application of dunhuang ancient medical theory.Result:In Dunhuang ancient medical prescription,compound 34 surgical diseases,collected and organized 42 groups of horn medicine,including sores,skin,breast,gall,gallstone disease and male prostate disease.Group 15 of corner drugs for treating sore diseases,Drugs to warm medicine,clear heat dryness and dampness medicine,clearing heat and cool blood medicine,warm solution table medicine,laxative medicine,blood tonic drugs,external insecticides,qi tonic drugs;Group 10,Drugs to xin wen solution surface medicine,blood circulation and remove blood stasis medicine,warm medicine,phlegm medicine,liver breath and wind medicine;Group 4,Drugs to clear heat and wet drugs,water infiltration wet medicine,qi medicine;Group 12,Drugs to benefit water infiltration wet medicine,warm medicine,tonic qi medicine,clear heat and cool blood medicine,collect astringent medicine,clear heat and diarrhea gunpowder;The horn drugs for treating breast disease and gall disease are mainly warm medicine and phlegm medicine,respectively.Angle medicine compatibility can be used for the same drugs,or for different drugs,forming a 2:1,1:2,1:1:1 structure,and can also be relatively compatible,such as Yin and Yang,qi and blood,zang and fu,etc.A group of corner drugs can appear as the main part or secondary part in the combination,or three Chinese medicines can be formed into their own.At the same time,Dunhuang ancient medical medicine is widely used,the same group of corner medicine can be compatible in different prescriptions.The application of temporary evidence is good at treating blood,wind,collect sores and muscle,qi and blood,Yin and Yang,clear three coke,warm spleen and kidney,liver,spleen and kidney and other horn medicine.Temporary treatment has a unique way of medication,especially all kinds of external treatment,such as paste,powder,tincture,anal suppositories,etc.Through data mining method,found that the cold,warm and spicy,bitter medicine is used high frequency of drugs,and spleen,stomach,lung three close relationship,by setting the appropriate support and confidence,it is concluded that three drug combination article 34,28 associated rules,including thin + attached + angelica,licorice +rhubarb + scuqin two groups of drug confidence is 1 and the highest frequency,the above are all clinical treatment surgical disease broaden the medication.Conclusion: Dunhuang ancient medical set compatibility of refined profound amazing,many horn medicine combination,based on data mining medicine set rule and horn medicine blending,its clinical application has high practical value,for clinical treatment of surgical diseases and research and development of medication provides a lot of new ideas,worthy of further application and research of modern medicine. |