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Exploring The Medication Rules Of Professor Zhang Yan In The Diagnosis And Treatment Of Chronic Heart Failure Based On Data Minin

Posted on:2023-08-22Degree:MasterType:Thesis
Country:ChinaCandidate:X N SunFull Text:PDF
GTID:2554306851468514Subject:Integrative Medicine
Abstract/Summary:PDF Full Text Request
Purpose:Collect and organize the medical records of Professor Zhang Yan’s diagnosis and treatment of chronic heart failure,use the modern technical means of data mining,summarize and summarize Professor Zhang Yan’s medication rules and treatment experience in the treatment of chronic heart failure,and inherit Professor Zhang Yan’s academic research on the diagnosis and treatment of chronic heart failure Experience.Material and Method:Collect the clinical data of 200 chronic heart failure patients admitted by Professor Zhang Yan in the specialist outpatient clinic of the Affiliated Hospital of Liaoning University of Traditional Chinese Medicine from December 2019 to December2021.Statistical software was used to mine clinical data.Through the analysis of frequency,frequency,correlation and clustering,the general condition,primary disease,co-morbidity,cardiac function classification,serum NT-pro BNP value,clinical symptoms and distribution of tongue and pulse of patients were summarized,the frequency of medication was counted,and high The association rules and clustering rules of frequent drug use are summarized and inherited from Professor Zhang Yan’s experience in the diagnosis and treatment of chronic heart failure.Results:1.General information: Of the 200 patients included in this study,112 were male(56%);88 were female(44%),with a male-to-female ratio of 1:0.79;the age distributio n of the patients was 18-98 years old,Mean 66.2±14.08 years.2.Disease situation: The top three primary diseases are coronary heart disease,high h eart disease,and pulmonary heart disease,accounting for 50.5%,21.5%,and 7.5%;Ab normal,accounting for 21.5%,16% and 12% respectively;83 cases of NYHA grade I I,78 cases of grade III,25 cases of grade IV,and 14 cases of grade I,accounting fo r 41.5%,39%,12.5% and 7%;serum NT-pro BNP value was negatively correlated wit h cardiac function.3.Symptoms and distribution of tongue and pulse: There are 65 kinds of symptoms,with a total of 1528 occurrences,of which shortness of breath,chest tightness,palpitat ions,mental fatigue,chest pain,asthma,lower extremity edema,dizziness,difficulty fa lling asleep,and low voice are the top ten most frequent occurrences.Symptoms: The re are 10 kinds of tongue signs,8 kinds of moss signs,and 10 kinds of pulse signs.The top 5 tongue symptoms with the most frequent occurrences were red tongue,dark tongue,pale tongue,petechiae and ecchymosis,and fat tongue;the top 5 moss sympt oms with the most frequent occurrence were white coating,thin coating,and little coa ting Moss,greasy moss,yellow moss;the top 5 pulse symptoms with the most freque nt occurrences were thin,stringy,slippery,several,and deep.4.Medication: 200 first-diagnosed prescriptions for patients with chronic heart failure were collected this time,and a total of 136 kinds of traditional Chinese medicines we re used,with a total of 2766 times,with an average of 13.83 prescriptions per prescri ption.The top 10 most frequently used traditional Chinese medicines were Poria,Ang elica,Chuanxiong,Astragalus,Tinglizi,Atractylodes,Guizhi,Baishao,Wujiapi,and Sal via.A total of 17 types of traditional Chinese medicines were used,and the top 5 typ es of traditional Chinese medicines with the most frequent applications were tonic,blo od-activating and stasis-removing,phlegm-relieving,cough-relieving and asthma-relievin g,heat-clearing,and qi-regulating.5.Correlation analysis results: Professor Zhang Yan’s commonly used drug combination s for the treatment of chronic heart failure are Albizia Julibrissin-Shouwu Teng,KeelOyster,Tinglizi-Wujiapi,Poria-Psyllium,Citrus aurantium-Hopu,Gualou-Xiebai-Pin ellia,Poria-Polyporus-Atractylodes,Poria-Polyporus-Guizhi,Tinglizi-Wujiapi-Motherwort,Ginseng-Ophiopogon japonicus-Schisandra,Tinglizi-Wujiapi-Aco nite-Poria,keel-oyster-habitat-Ophiopogon japonicus,tangerine peel-Pinellia-Citrus aurantium-Magnolia officinalis,Poria-Guizhi-Atractylodes-Licorice,Astr agalus-Angelica-Chuanxiong-Salvia,etc.6.Cluster analysis results: Professor Zhang Yan’s four high-frequency clusters in the tre atment of chronic heart failure are: prescription 1: keel,oyster,ginseng,Ophiopogon j aponicus,schisandra,shengdi,licorice,paeonol,red peony;prescription 2: angelica,ch uanxiong,Astragalus,Salvia: Prescription 3: Poria,Atractylodes,Pinellia,tangerine pe el,Citrus aurantium,Magnolia,Jiao Sanxian;Prescription 4: Tinglizi,Wujiapi,Guizhi,Baishao.Conclusion:1.The incidence of CHF is mainly the elderly,and the incidence rate increases with age.2.Coronary heart disease and high heart disease are the main primary diseases of CHF;type 2diabetes mellitus and hyperlipidemia are common comorbid diseases of CHF;NYHA cardiac function classification is mainly grade II and grade III;serum NT-pro BNP value is significantly correlated with cardiac function.negative correlation.3.Shortness of breath,chest tightness,palpitations,and fatigue are the four main symptoms of CHF.4.Prof.Zhang Yan believes that the pathological nature of CHF is deficiency and excess,the primary deficiency is deficiency of heart qi,and the excess is mostly phlegm-dampness,water-drinking,and blood stasis.5.Professor Zhang Yan believes that in the early stage of CHF,the syndrome of qi deficiency and blood stasis is common,and the treatment is often based on the method of nourishing qi,activating blood,and strengthening the heart and dredging the pulse;The method of promoting blood circulation and dredging collaterals;in the late stage of CHF,the syndrome of yang deficiency and water is more common.
Keywords/Search Tags:data mining, chronic heart failure, medication rules, Zhang Yan, experience inheritance
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