Foundation Of Horse Synthesis Database Of China And Prediction Of Horse Genome Sequence

With the development of modern biology and a growing accumulation of biological data, a new field of biology-Bioinformatics emerged. Bioinformatics involves applications of the theories and technologies of informatics to biological data analysis and management, and it is a multi-misciplinary research field relating to mathematics, physics, computer science, chemistry and biology. The research of bioinformatics ranges widely and one of the most important fields is database development. And it is an important task for bioinformatics to recoganize and predicts exon and intron using theory and calculation methods.This topic has found the network databases of china horse resources by using programs compiled by us named Horse Synthesis Database of China www.chinahorse.org.cn. Based on network databases, some primary applications of the databases have already been done, including network of bibliographic database based on Web and so forth. These would benefit for the foundation of science research platform of horse breeds resource. The detail information is as follows:1. Specificity, systematic and complete horse science database is established. The sequence libraries mainly include Gene Database and Protein Data Bank. The non- sequence library mainly include Bibliographic Database and Picture Database. The records of Horse Gene Database have over 20,000 and the records of Horse Protein Database have over 30,000.2. The database of Chinese indigenous horse breeds is established. The contents of databases involve their exterior, color and typical characters. The databases would provide some useful information to utilization and protection of Chinese horse breeds.3. Bioinformatacs platform of horse can research genes and their associate features, can simulate protein and there-dimension structure as well. The beautiful output images are easy for educational use and complicated researches.4. Established a horse science and industry of laboratory web and BBS of horse industry. It can be searched by the internet and enhanced the application efficiency of database. Website is a tool of communications, meanwhile, is a platform to update these databases. In this study we did a preliminary statistical analysis on codon usage in the entire horse genome sequence and the intron and exons were predicted. Based on a variety of the different components of the sequence and the conservative character of start and end of the sequece, this study combines the use of increment of diversity and support vector machine method to identify horse genome intron and exon sequences. Based on the single base, diad and triad frequency of use, we are able to correctly predict more than 91% of the intron and exon.