Clinical Study On The Application Of Asthma Therapy In Children With Asthma And Breath Sounds

Objective:System evaluation of clinical efficacy of relieving asthma massage in the treatment of childhood asthma, including acute exacerbation of antiasthmatic effect and effect of prevention and control of chronic duration. Offerring an effective and safe, simple treatment and prevention options in childhood asthma treatment. Quantitative analysis on the changes of respiration signal in asthmatic children, Spectrum analysis of respiratory sound signals in acute phase of asthma, chronic persistent period and normal children. To provide a new clinical diagnosis and treatment method for quantitative monitoring and recording theMethod:1. By using the self-control research methods,60 cases with acute phase of childhood asthma were collected. Changes in children with symptoms, signs, respiration sound and PEF, FEV1 were observed before and after Relieving asthma massage therapy, by then we evaluated the curative effect of relieving asthma massage on acute stage.2. We collected 140 cases and randomly divided into the treatment group (manipulation+traditional Chinese medicine treatment group) and control group (traditional Chinese medicine treatment group),70 each and between the two groups of parallel control. We observed in children with symptoms and signs, childhood asthma control testscore (C-ACT), PEF, FEV1, respiration sound intensity and total effective power on the day of admission and followed up for 1-6 months,. To evaluated relieving asthma massage on curative effect of chronic persistent period. Symptoms recurrence appared reduction3. Using 3MTM Littmann r 3200 electronic stethoscope to recording respiratory sounds of asthma at acute stage, The amplitude of respiratory audio spectrum showed significantly elevated in each frequency section in acute childhood asthma。 asthma chronic persistent period and normal children. And extracted respiration related data with a supporting software, quantitative analysised the respiration sound intensity, the total effective power and respiratory audio spectrum,.Results:1. Compared before and after treatment, cough, chest tightness, dyspnea, panting, suffocation were significantly reduced (P<0.05); Wheeze compared with before treatment was significantly reduced, some wheeze even disappeared (P<0.05); Respiration strength decreased obviously (P<0.05), The total effective power is obviously reduced (P<0.05), And a significant increase in PEF, the value of FEV1 (P<0.05). Manipulations in the treatment of acute attack of asthma in children have significantly effect.2. The two groups the baseline is consistent, with comparable. according results from 6 month follow-ups observation point of time, The full analysis set (FAS) and per protocol set (PPS) results are basically consistent, reliable results. the treatment group can effectively control the chronic persistent asthma symptoms more than the control group, no significant difference of PEF, FEV1 changes between the two groups (P>0.05), but the average treatment group was higher than that of control group. The treatment group was significantly lower than the control group in the respiration intensity and the total effective power (p<0.05). C-ACT score of treatment group was significantly higher than the control group (p<0.05). Overall, the treatment group significantly than the control group, the effect is remarkable of children asthma chronic persistent period.3. the cases of acute period, chronic persistent period is significantly higher than normal children in respiration sound intensity and the total effective power (p<0.05). Compared with chronic persistent asthma respiratory audio spectrum and normal children. Only at some frequencies of sound intensity is higher (p<0.05).Conclusion:1. asthma massage method can alleviate the acute asthma symptoms, improve pulmonary ventilation, treatment of children asthma acute attackeffect is remarkable。2. To chronic persistent asthma in children, massage can effectively control symptoms, relapse prevention, reduce airway resistance, improvepulmonary ventilation, the effectiveness in the treatment of child asthma chronic persistent period significantly.3. Through a comparison of respiratory sound signals between the acute phase of asthma, chronic persistent period and normal children with, Discovered that respiratory audio spectrum analysis can reflect the pulmonary slight changes. Respiratory audio spectrum analysis is a more sensitive and objective index.