A Study On The Related Documents Of TCM Syndrome And Drug Administration Of Coronary Heart Disease And Angina Pectoris

Purpose：1.Discusses the quantitative diagnosis of syndromes of coronary heart diseaseand angina pectoris, initially realizes the quantitative diagnosis of coronaryheart disease and angina pectoris.It establishes a common objective andeffective science TCM syndrome diagnosis model, and provides a statistical basisfor angina pectoris of coronary heart disease of TCM.2.Explores the law of clinical syndrome differentiation and treatment. It mayprovide theoretical basis and objective basis for clinical and scientificprescription in treating coronary heart disease angina pectoris of future.Material and method：With searching words "angina pectoris of coronary heart disease","chest","heartache",the second key words of "syndrome","differentiation","differentiation","Chinese medicine treatment", I search and downloadliterature of coronary heart disease and angina pectoris published in domesticcore journals of literature through China biomedical literature database(CBMdisc). For literatures of a directory without full text, I take the manualretrieval of Liaoning University of Traditional Chinese Medicine libraryperiodical magazine to find it, and there were489papers in all. Accordingto the literature of inclusion and exclusion criteria, I get25papers,3090cases of drug laws,21literatures,1786patients.which meet the standards ofthe TCM Syndromes.At first, statistics is the theoretical foundation of data mining technologyapplication technology,now has been widely applied to the field of medicalresearch. The method of the main topic are the use of sorting, frequency, Logisticregression analysis, maximum likelihood models. Using logistic regressionanalysis method, to screen the related factors, and find out the common syndrome factors, then using the maximum likelihood method,to establish quantitativediagnosis table of common coronary heart disease syndromes, and finally is thefurther back substitution test.The results show that, the quantitative diagnosistable shows a good sensitivity, specificity degree, accuracy, positive andnegative likelihood ratio, the quantitative standard, This shows that thequantitative standard of the quantitative diagnosis table reach an agreementwith national standard or experts consensus.Results：1.Through the results of the statistical analysis, the most common syndromesof angina pectoris of coronary heart disease can be preliminarily determined:Heart qi deficiency syndrome, blood stasis syndrome, phlegm syndrome, Qi Yinheart pulse two deficiency syndrome, heart yang deficiency, cold stagnation ofheart vessel syndrome, heart Yin deficiency syndrome.And heart Yin deficiencysyndrome in angina pectoris of coronary heart disease is rare.After furtherresearch, quantitative diagnosis table of the7syndromes was established andto determine the diagnostic threshold.2. In coronary heart disease angina pectoris nearly100Chinese herbal from100compound is studied. The therapy can be summarized as follows: Xinwentongyang、xiezhuohuotan、promoting blood circulation to Eliminat pathogens and treat theroot cause;invigorating Qi and warmingYang、supplementing qi and nourishing yinand nourishing the kindney and liver to strengthen the body resistance.Itinvolved a total of104drugs, and a using of19604times, the average of eachmedicine was188.5times,33drugs used more than188times, they were seen15276times, and77.9%times of the total drug. We call them the high frequency druguse. ainly Chinese angelica, Rhizoma Chuanxiong, radix salviae miltiorrhizae,radix paeoniae rubra, safflower, peach kernel, licorice, astragalus, Codonopsispilosula, snakegourd fruit, cassia twig, bulbus Allii, bitter orange, tuckahoe,radix curcumae, Radix Ophiopogonis, three seven,Schisandra, raw land, largeheadatractylodes rhizome etc.And get the drugs’ using times of different types and higher frequency, summed up the top twenty Chinese herbs.Conclusion：1.Initially identified the most common syndromes of angina pectoris of coronaryheart disease: heart qi deficiency syndrome, blood stasis syndrome, phlegmblocking heart vessel syndrome, heart Qi and yin deficiency of heart yangdeficiency syndrome, two, cold stagnation of heart vessel syndrome, heart Yindeficiency syndrome.Heart qi deficiency syndrome, blood stasis syndrome, phlegmblocking heart vessel syndrome, are the main types of angina pectoris of coronaryheart disease.Therefore, we should be Yiqi Huoxue Huatan Tongluo, runs throughthe treatment of coronary disease angina pectoris,It also evidents the coronaryheart disease and is angina pectoris standard virtual reality based card,andthe heart qi deficiency is the Ben s,tagnation of Qi、phlegm and blood stasis,are Biao, the treatment principle to strengthen the body resistance.Whatobtained the angina pectoris of coronary heart disease syndromes are consistentwith textbooks and the conclusion of National Conference.2.It established the quantitative diagnosis table of coronary heart diseasesyndromes,and provided a model for the clinical diagnosis and differentialdiagnosis.The table showed good sensitivity, specificity, accuracy, positiveand negative likelihood ratio, proved the quantitative standard of thequantitative diagnosis table has good discrimination ability.3.It confirmed disease and syndrome of TCM can be standardized and quantitative.And got TCM syndrome differentiation typing schem of coronary heart disease andangina pectoris,which rovides a better model for the clinical diagnosis. Butthe research method is still to be improved, and needs a further clinicalvalidation.4.Coronary heart disease and angina pectoris medication coverage is wide, butthey more concentrated in the Qi, nourishing Yin, activating blood, regulatingqi, warming Yang, phlegm drugs. The therapy can be summarized as follows:Xinwentongyang、xiezhuohuotan、promoting blood circulation to Eliminat pathogens and treat the root cause;invigorating Qi and warmingYang、supplementing qi andnourishing yin and nourishing the kindney and liver to strengthen the bodyresistance. The study gets high-frequency appearance drugs of the coronaryheart disease and angina pectoris, and the most commonly used drug is also thekinds above.At the same time,we get drugs with different syndrome type drug timesand higher frequency, and sum up the top twenty Chinese herbs,which can be thefirst choice in the treatment of angina pectoris of coronary heart disease.