| In traditional Chinese medicine, Ischemic Cerebral Vascular disease that categorized into wind stroke shows high rate of attack, death and disability, the prevention and treatment of which is an important subject on medicine and society for it?s terrible harm to people?s health. Acupuncture for ischemic stroke is much better than other treatments with convenience, availability, cheapness and convinced by both experts and patients of ischemic stroke all over the world. In order to study the action mechanism of acupuncture and moxibustion in treating this disease more systema-ically and comprehensively, the following context has several aspects. J.Literature research Tracing the originals, from the appearance of Yellow Emperior?s Internal Medicine as the first classical works of traditional Chinese medicine to the dynasties of Tang, Shong, Yuan, Ming and Qing, the predecessors had done much to ancient medical books in the aspects of the stroke?s term, etiology, pathogenesis and therapy. In the late years, many articles carefully explain much research of the disease such as clinical experiments, ischemic cerebral injury of pathological and physiological basis in modern science and acupuncture effect. All that has been done founds the theorical basis of further studying acupuncture for ischemic stroke. 2.Experiments research Thinking of the mechanism of pathology and physiology about the cerebral ischemia injury, we take up focal cerebral ischemia by occlusion of the middle cerebral artery (MCAO) in the rat brain as the experiment model. In the course many methods were used such as electrophysiology, morphology, biochemistry, cytochemistry etc. With carefully studying the subsequential neuronal?s injury for cerebral ischemia after acupuncturing the Du channel?s acupoints, we can deduce some conclusions as the following: 1) The part cerebral blood flow in the ischemia district diminishes rapidly after keeping the rats focal cerebral ischemia forl0, 60 and 120 minutes, which shows therapy of electro? acupuncture is able to improve the region cerebral blood flow (rCBF) in the ischemia district and prevent the blood flow from decreasing. 2) A lot of free radicals have been produced in the brain without enough blood. The therapy of electro-acupuncture, however, can restrain the production of free radicals in ischemia districts, enhance superoxide dismutase?s (SOD) activity of cerebral tissues, reduce malonyldialdehyde's (MDA) content. Conse? quentialy it can prevent the injury of ischemia neuron, which caused by the reaction of lipid peroxidation. 3) The magnitude of nitric oxide (NO), nitrix oxide synthase (NOS) and endothelin?(ET-l) in the ischemia district of cerebral tissues goes up under cerebral ischemia. The electrotherapy can deteriorate this tendency so as to improve the cerebral blood flow and protect the ischemia neuron from being further injuried. 4) The nerve cells activity under cerebral ischemia is obviously restrained, but the electrontherapy can apparently improve the changes of spontaneous echoncephalography (EEG) and somatosensory evoked potential (SEP), so which proves that electrotherapy has the function of protecting the activity of nerve cells for cerebral ischemia. 5)...
|
PDF Full Text Request