Protective Function Research Of The Zhongfengkang On Nerve Cells Of Focal Cerebral Ischemia Rats

Objective: The Protective function of zhongfengkang on nerve cells of focal cerebral ischemia rats was proved, and furthermore its function mechanism was probed into through the animal experiment and on basic of model of focal cerebral ischemia rats.MethodsPart 1: The effect of zhongfengkang on nerve cells transparence and infarct volume of focal cerebral ischemia rats50 healthy rats in SD,the weight of 250-300 gs,were divided into four groups at random as examination of infarct volume,that is,model group, zhongfengkang high-dose group(call a high-dose group),zhongfengkang low-dose group(call a low-dose group) and Buchangnaoxintong control group(call control group),and each one takes 8 rats. It were divided into five groups at random as electric- microscope observation,that is,Sham operation group,model group,zhongfengkang high-dose group( call a high-dose group),zhongfengkang low-dose group(call a low-dose group) and Buchang -naoxintong control group(name control group),and each groups takes 3 rats. The rats of high-dose,low-dose group and control group were given medicine through watering stomach everyday from 5 days before operation to before death. The dose of zhongfengkang high-dose group is 18.8 g/ kg;The dose of zhongfengkang low-dose group is 9.4gs/kg;The dose of buchangnao -xintong group is 0.33 gs/ kg.The rats of sham operation group and control group were given 0.5% carboxymethylcellulose sodium liquid through watering stomach once a day.According to the report,To make the model of focal cerebral ischemia by inserting nylon thread,The rats belly were injected 10% chloral hydrate(the dose was 350 mgs/Kg),after anaesthesia,it were laied on the back and fixed,...