Research On Catecholamine Hormone's Effect On Expression Of The Peripheral Cellular Inflammatory Factor

Part OneBackground: The atherosclerotic process is the culmination of a number of events: endothelial injury; induction of adhesion molecules; adherence of platelets; recruitment of monocytes and lymphocytes which adhere to and permeate the arterial wall; appearance of proinflammatory cytokines; infiltration and oxidation of low-density lipoprotein; activation, movement, and hyperplasia of myocytes; formation of foam cells from macrophages and smooth muscle cells. One of the focuses of cardiovascular disease research is to study pathogenesis of atherosclerosis (As). At present, there are many theories about the pathogenesis of As, such as the fat infiltration theory, blood platelet aggregation and thrombosis theory, smooth muscle cellular clone theory and damage reaction theory. It is discovered in recent years that the pathological performance of As featured the basic form of inflammatory pathology. Along with continuous finding of inflammatory cells and media in atheromatous plaque, atherosclerosis has come to be recognized as active and inflammatory rather than simply a passive process of lipid infiltration or a reparative process after endothelial injury. Recently, many studies have demonstrated that psychosocial stress is a risk factor for cardiovascular disease. A large body of evidence, which indicates that psychosocial factors play some role in the etiology and progression of certain cardiovascular diseases such as atherosclerosis, has now been...