Study On Preparation And Properties Of Galactos-polyethylene Glycol-poly(L-lysine)/plasmid Enhance Green Fluorescent Protein Complexes Nanoparticles Micelle

Liver is the biggest digest gland and indispensable metabolize center of human body which is related closely to many hereditary diseases,metabolize diseases,tumors. For example liver cancer, it can be cured only to 15% by surgery and is insensitive by chemotherapeutic and actinotheraphy, others is not ideal. Therefore, in near several years, with the development of the biology of molecule and recognition of liver disease mechanism, many researchers introduce gene therapy into all kinds of liver diseases therapy. Gene therapy is a method that exterior gene is come into aim cell and can be efficient expression.[0] Efficient delivery of foreign DNA into cells is an extremely critical step in gene therapy. To avoid using viral vector systems that may elicit undesirable safety problems, non-viral vector systems are an attractive alternative method to deliver DNA into cells. Increased attention has been given to non- viral...