The Role Of Radionuclide Renal Imagings In The Diagnosis And Treatment Of Renovascular Hypertension

Captopril renography has been accepted as a non-invasive method for evaluation of renovascualr hypertension. But some reports have some discrepancy on the sensitivity and specificity for diagnosing of renovascular hypertension. The aim of this study was to evaluate the clinical value of losartan test for diagnosing of renovascular hypertension and compared with captopril test.Materials and methodsStudy population46 patients with suspected of renovascualr hypertension between October 2000 and December 2001 were studied. Among them, 15 men and 31 women, average age 42.3 ± 16.4 years old. All patients underwent radionuclide renography with captopril and furosemide intervention. After that, losartan renography was obtained 24 hours later. All patients had renal artery angiography within 7 days after radionuclide renography. The percutaneous transluminal renal angioplasty (PTRA) and percutaneous transluminal stenling placement (PTSP) were performed in 10 patients, single PTRA was performed in one patient. The retrospective analysis125 patients who had both captopril renography and renal artery angiography were retrospectively analyzed. Among them, there were 71 male and 54 female with an average age of 35.8±13.6 years old. 19 patients had PTRA and PTSP, 8 patients had only PTRA, 3 patients underwent renal artery autografting.171 patients were divided into three groups :Group A: 46 patients had both captopril and losartan renographies. Group B: 72 patients had captopril and furosemide renographies. Group C: 53 patients had only captopril renography.