Experimental Research Of Immunological Prevention And Therapy Of Colorectal Cancer

ForewordColorectal cancer is one of the most familiar malignant neoplasms. The low early diagnosis rate of colorectal cancer is one of the mostly reasons resulting a low curable. To develop a new approach for the early diagnosis of colorectal cancer, radiolabelled chimeric antibody against human carcinoembryonic antigen (CEA) was used in radioimmunodetection of colorectal cancer. To advance the time of the radioimmunodetection with intact chimeric antibody a small molecular antibody was constructed and high level expressed in CHO-dhfr" cells, and the radioimmunodetection with it was also done. That colorectal cancer is prone of metastasis and recurrence is another mostly reason of high mortality and low 5-years survival rate of colorectal cancer patients. There was no efficient clinic therapy approach for the metastasis and recurrence of colorectal cancer until now. To develop a new approach to...