| For the purpose of clarifying the confusion around chronic myelomon-cytic leukemia(CMML), we made a retrospective analysis of 35 cases of CMML diagnosed at our hospital between Jun. 1985 and Oct. 1995,according to the criteria of FAB cooperative group (FAB criteria). Two groups with different clinical and hematological characteristics, CMML —A and CMML —B, were identified. There were statistically significant differences between the CMML—A and CMML—B in white blood count (WBC 33. 60 ±21.16 vs 6. 36±2. 46, 10?/L,p<0. 01),hemoglobin (97. 89±26. 21 vs 74. 55±20. 0, g/L, p<0. 01), platelets(138. 42±91. 0 vs 54. 66±25. 52, 10?/L, p<0. 001), reticulocytes (2. 54%±0.7% vs 0. 80%±0. 38%.P <0. 05),percentage of immature granulocytes in peripheral blood (4. 68% ±3. 60% vs 0. 30%±0. 99%, p<0. 05), percentage of granulocytic lineage in bone marrow (73. 30%±10. 48% vs 50.16%±14. 97%, p<0. 01) and the percentage of erythroid precursors in bone marrow (11. 65%:±5. 65% vs 34. 28%±14. 08%, P<0. 01). Moreover, the cellularity of bone marrow and the dysplastic features of hematopoietic cells also differed markedly between the two groups. In CMML—A, the bone marrow was always extremely hypercellular,and the dysplastic features were minute or confined to granulocytic precursors ; while in CMML—B, the marrow hypercel-lularity was to be lesser extent, and the dysplastic features were prominent and generally trilineal. It is evident that the characteristics of CMML —A accorded with that of myeloproliferative disorders (MPD), and the characteristics of CMML—B, myelodysplastic syndromes (MDS).We further divided CMML —B into two subgroups, CMML — B1 and...
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