Functional Dyspepsia Syndrome Distribution And Quality Of Life Status In Evaluation Studies

Objective:This study aimed to explore the characteristics of the traditional Chinese medicine (TCM) syndrome, and the distribution of syndrome of functional dyspepsia (FD) under the explanation of the theory of TCM. It provided the guidelines to clinical treatments for FD in the future following evaluating the condition of quality of life, as well as the severity of depression and anxiety determined from FD patients.Methods:A total of 113 subjects were recruited from patients with FD visiting at outpatient clinic of digestive medicine in Dongzhimen Hospital. After obtaining written consent, the FD patients themselves filled up four kinds of reliable questionnaires, such as Investigative Table of FD Syndrome, SF-36, Zung's SDS, and Zung's SAS, anddirected by a physician nearby. All data were keyed into the Microsoft Excel for subsequent calculations. Proportions of sex, nation, age, body height, body weight, marriage, vocation, food preference, cigarette preference, alcohol preference, cultural level and hypersensitivity to drug were analyzed. Which type of TCM type identification of FD was determined by the scores of symptoms of TCM and Western medicine. Scores of SF-36, SDS, and SAS of each patient were also calculated. Same TCM type identification of FD patients was collected together. Means and standard deviations of scores of SF-36, SDS, and SAS of every TCM type identification were then measured. Finally, the highest score of SF-36 and lowest scores of SDS as well as SAS of TCM type identification were interpreted.Results:Among TCM types identification of FD, there were not statistically significant differences in sex, age, marriage, nativity, and vocation of all study subjects (p>0.05). Epigastric fullness, postprandial distention, poor appetite, belching of gas, lassitude and epigastric pain were most frequently suffered in TCM symptoms of FD. In food preference, the proportion of eating chili pepper subjects was 37.2%, while the proportion of touching alcohol subjects was 23%. In four TCM types identificationof FD, the frequencies of their individual distribution regulation were as follows: dampheat-crowd-stagnancy was 17.7%, spleen-vacuity-current-stagnancy was 20.3%, liver-stomach-current-stagnancy was 25.3%, liver-stomach-depression-heat was 36.3%. There were not significant differences in proportions of body height, body weight, cultural level, food preference, cigarette-alcohol preference, and hypersensitivity to drug(p> 0.05). In TCM type identification of FD, there were significant differences in various symptoms attributing to TCM and Western medicine (p<0.01). The proportion of depression patients was 54% of subjects, while the proportion of anxiety patients was 28.3%. In four types of TCM syndromes of FD, the score of SF-36 in spleen-vacuity-current-stagnancy was 68.71±28.04, whereas the score of SDS was 43.75±8.07, and the score of SAS was 40.16±6.93.Conclusions:There were not correlations between distribution of TCM type identification of FD and sex, age, body height, BMI, marriage, cultural level, as well as food preference. There were close correlations with distribution of TCM type identification of FD and TCM symptoms, symptoms of Western medicine, images of tongue and pulse, quality of life, depression, as well as anxiety. Liver-stomach-depression-heat and liver-stomach-qi-stagnancy were more frequently occurred in TCM type identification distribution of FD. The scores of SF-36, SDS, and SAS were most favorably appeared in spleen-vacuity-qi-stagnancy listed in TCM type identification distribution of FD.