Distribution Rule Of Syndrome Differentiation In Traditional Chinese Medicine In Functional Dyspepsia

Objective:This study was forward-looking research to understand the distribution rule of syndrome differentiation in Traditional Chinese Medicine in Functional Dyspepsia in Guangzhou, and observed the relationship between functional dyspepsia syndromes and gastric emptying, gastrointestinal hormones, psychological factors, so as to guide the treatment of functional dyspepsia, and lay the foundation for the development of Chinese medicine preparations.Methods:In Guangzhou hospital of TCM Department of Gastroenterology, wo collected 150 patients with functional dyspepsia, using epidemiological survey methods, to fill in the questionnaire cases, parallel examination of gastric emptying, gastrointestinal hormone testing, as well as fill in SAS, SDS score sheet, observation of their age, sex, gastric emptying, gastrointestinal hormones, psychological factors and other factors and the relationship between TCM syndrome distribution; and select 30 healthy volunteers as controls, gastric emptying and gastrointestinal hormone understand the situation.Results:1,Among different types of FD,43.33% are weakness of spleen and stomach type,25.33% are liver—stomach disharmony type 12.67% are Damp-heat type, 8.67% are food stagnancy type, and 10% are cold and heat mixed type; for different distributions of FD syndrome pattern, there is no statistical meaning with the patients' age and sex(P＞0.05);2,The relationship between FD of syndromes and gastric emptying rate FD patients with gastric emptying rate of the value 0.45±0.29, lower than the healthy volunteers, the difference was significant (P＜0.05), evidence-based FD patients with different gastric emptying rate, the difference was significant (P＜0.05), liver-stomach disharmony type below the spleen and stomach type, the difference was significant (P＜0.01), comparison Damp-heat type, cold and heat mixed type, food stagnation-type and weakness of spleen and stomach type, the difference was not significant (P＞0.05); Damp-heat type and food stagnancy type were higher than liver-stomach disharmony type and the difference was significant (P＜0.05); Comparison cold and heat mixed type, food stagnancy type and Damp-heat type, the difference was not significant (P＞0.05); food stagnation-type and cold and heat mixed type, the difference was not significant (P＞0.05).3,The realationship between FD of syndromes and gastrointestinal hormones compared with healthy volunteers, MOT, GAS was lower than the healthy volunteers, the difference was significant (P＜0.05) SS, VIP was higher than healthy volunteers, the difference was significant (P＜0.05), FD syndromes in patients with SS, VIP was higher than healthy volunteers, the differences were significant (P＜0.05), GAS and healthy volunteers rather, the difference was not statistically significant (P＞0.05); MOT in Weakness of spleen and stomach type, Damp-heat type, cold and heat mixed type was almost equal with healthy volunteers, the difference was not statistically significant (P> 0.05), MOT in liver-stomach disharmony type and, food stagnancy type in patients with FD was lower than healthy volunteers, the difference was significant (P＜0.05).4,The realationship between FD of syndromes and psychological factors Compared different syndromes with the national norm, which showed significant (P＜0.05), between the various syndromes, the difference was significant (P＜0.05); SAS:Compared liver-stomach disharmony type, food stagnancy type and weakness of spleen and stomach type syndrome, the difference was not significant (P＞0.05), Compared Damp-heat type, cold and heat mixed-type and weakness of spleen and stomach type, the difference was significant (P＜0.05); liver-stomach disharmony type was higher than Damp-heat type and cold and heat mixed type, the difference was significant (P＜0.05), compared food stagnation type between liver-stomach disharmony type and cold and heat mixed type, there was no significant difference (P＞0.05); SDS:compared liver-stomach disharmony type and, cold and heat mixed type, food stagnation type and weakness of spleen and stomach type, the difference was not significant (P＞0.05), weakness of spleen and stomach type and Damp heat type, the difference was significant (P＜0.05); Damp-heat, food stagnation type, cold and heat mixed type lower than liver-stomach disharmony type, the difference was significant (P＜0.05), cold and heat mixed type and food stagnation type, the difference was not significant (P＞0.05)Conclusion:1,Distribution Rule of Syndrome Differentiation in Traditional Chinese Medicine in FD in Guangzhou, weakness of spleen and stomach type and liver-stomach disharmony type were most, and there was no realationship between age sex and Different FD syndrome pattern2,FD patients had significantly delayed gastric emptying, and the liver-stomach disharmony type was the most serious.3,FD patients with gastrointestinal prokinetic hormones decrease, increase inhibitory gastrointestinal hormone, FD patients with delayed gastric emptying may be the main mechanism and the different syndromes are different levels of gastrointestinal hormones.4,FD patients prone to anxiety, depression, which liver-stomach disharmony type and weakness of spleen and stomach type of the highest rates of type...