Clinical Study Of Effects Of Anti-inflammatory On On The Lumbar Disc Herniation Treated By Electroacupuncture Combined With Medicine-dimensional Points

Objective:The basic theory of traditional Chinese medicine combined with modern research results, through the establishment of lumbar disc herniation surgery rat model of drug-dimensional observation of acupuncture points combined with external application of lumbar disc herniation model of nerve root compression of nerve roots in the pathological changes of the local, thromboxane B2 (TXB2)/prostacyclin Flα(PGF1α)content changes. Preliminary study medicine acupuncture points combined with external application of law dimension in the treatment of lumbar disc herniation in the anti-inflammatory and analgesic mechanism for deeper study provides the basis of preliminary studies.Method:Select the Sprague-Dawley (SD) 60 rats, weighing 180～200g, male and female. Copy lumbar nerve root compression model in rats, divided into control group, model group, EA group, drug group and EA D + D drug group five. N=12, male and female. Treatment after the end of treatment were compared among groups of nerve roots in the pathological changes of plasma thromboxane B2/prostaglandin PGF1αnerve activity levels and behavior ratings.Result:1 Rats by EA, EA Garvey Victoria drugs and drug therapy, plasma TXB2 levels and TXB2/PGF1a ratios were significantly decreased (P <0.01), while the PGF1a level was elevated (P<0.01), showed a positive change. Compared with model group, both the EA group, Victoria EA+ drug group or drug group D, the P values were<0.01, significant difference in the results, indicating that the three treatments had good effect; EA + dimensional drug group were compared with the EA group and medication group D compared with the P<0.05, significant difference, but EA group and medication group D P> 0.05, two treatments that have good synergy2 Score of neurological behavior in rats showed that compared with the model group, both the EA group, Victoria EA + drug group or drug group dimension, the general view of experimental rat limb score was significantly decreased, the P values were<0.05, the results significant differences, indicating that three kinds of treatments have good results; EA + D drug group were compared with the EA group and medication group D compared with the P<0.05, significant difference.Pathological observations in rats after the modeling of nerve root compression of nerve tissue, see mild interstitial edema, a little more blood vessels, mononuclear inflammatory cell infiltration and a small amount of fibrous tissue proliferation, some of nerve atrophy; by EA, Victoria medicine, electricity IF acupuncture treatment, the lesions improved ratings have dropped, in which EA group, EA Garvey drug group and model group were P<0.01, lesion score three groups were from low to high power Garvey medicine acupuncture group, EA group, Victoria drug group.Conclusion:Electroacupuncture combined with acupoint-dimensional medicine is a topical treatment of lumbar disc herniation clinical effective method; same time, the method can effectively reduce the rat model of lumbar disc herniation. Then show that the method of lumbar disc herniation rats with anti-inflammatory and analgesic effect.