Cerebral Infarction Risk Factors And The Microscopic Dialectical Yiqihuoxue Efficacy Mechanism

The Dangerous Factor and Microcosmic Differentil Diagnosis of Cerebral Infarction and the Research of the Therapeutical Effectireness Mechanism of the Therapy Supplementing qi and Actirating Blood Circulation. Doctor Degrees Postgraduate :He yun he Director:Guo zhen qiu AB S TRACT Cerebral infarction is the most common disease of blood vessel of brain. We Researched it systematically from the four parts: Document of TCM, Clinical symptom investigation, Clinical research of therapeutical effectiveness and animal experiment. 1. The recovery of the pathogenic factor and pathogenisis and the regular rule of diagnosis and treatment of document indicated that celrebral infarction belongs to apoplexy was internal dificiency pathogenic factor梥troke and endogenous wind. The basic pathogenisis were imbalance of yin and yang, reversed flow of qi and blood, uplexy and hemormagic apoplexy. The therapy was developed from internal dificiency pathogenic factor梥trake treated by invigorating qi and enriching the b1ood~ expelling the wind and removing the dampness to dificiency of blood with sputum treated by remoring the sputum first, untill recently up-stirring of lirertreated by nourishing yin and supplementing blood. Calmig the liver to stop the wind and dificiency of qi and blood stasis treated by supplementing qi and activating blood circulation. Nowadays the therapy varied into polypyly and the blood stasis of ischemic apoplexy was especially strenthened, better clinical therapy of Traditional Chinese Medicine with the function of supplementing qi and actirating blood circulation was discovered. 2. Investigation to the Clinical Symptom: After the investigation to the clinical symptom of 316 cases of patients with cerebral infarction, We 4 Lt discovered that: The disease incidence of male was higher than that of female and hypertension was the main dangerous factor of cereral infarction. The main clinical TCM symptom complex was dificiency of qi and blood stasis. Most of the patients this of this mode had the case history of heart diseases and diabetes, the ischemic region was mostly basal ganglion, the myodynamia of limbs was mostly 0?I and the serum enzyme CK~ whole blood viscosity were clearly elevated. The followed TCM symptom complex was hyperactivity of yang due to yin deficiency. The patients of this mode almost had the case history of hypertension, the ischemic region was mostly posterior crus of internal capsule, the serum Cr~ BUN and serum enzymy LDH. r-GT~ AKP were clearly higher than the other symptom complex modes. Then followed the mode of stagnation of phlegm and stasis in the interior. The ischemic region was mainly temporal lobe, its blood LDL-CH~ TCHO~ TG~ RBC clustering rate. Pt adherence rate and fibrinogen were clearly elevated. These indexes in the upper modes had significant differences with the other modes and could be adopted as the evidence of the microcosmic differentil diagnosis of the mode in clinic. 3. Clinic observation: The research of clinical therapeutical effectiveness to 72 cases of patients of cerebral infarction with TCM differention of symptoms and signs difficiency of qi a...