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Polygalaceae Resources And Quality Of Evaluation Research

Posted on:2007-12-22Degree:DoctorType:Dissertation
Country:ChinaCandidate:G Z WangFull Text:PDF
GTID:1114360185985277Subject:Pharmacy
Abstract/Summary:PDF Full Text Request
Yuanzhi,Radix Polygalae, the dried root of Polygala tenuifolia Willd. or P.sibirica L. (Polygalaceae), is widely used in Traditional Chinese Medicine(TCM) for a long history . It is used not only as an expectorant and antitussive, but also as a sedative for the treatment of palpitations and insomnia due to anxiety, It can lower blood pressure, improve the function of brain, boost physical strength and intelligence. It also has the effect of anti-inflammation and anti-mutation. With its wild resources destroyed and decreased, it is now planted widely in Shanxi, Shannxi and Gansu Province of China. In order to protect and utilize the resources of P. tenuifolia Willd. and P. sibirica L. reasonably, investigation on wild resources must be carried out. What's more, the quality of wild and cultivated Radix Polygalae as well as processed slices needs appraised, which can assure the safety and efficiency of the drugs used in clinic.Systematical herbalogical study was investigated in this paper and the name as well as medicinal history, medicinal variety , habitat and geoherbalism of Yuanzhi was clarified. The properties and efficiency, compatibility and indications of Yuanzhi was analyzed and the technic of picking and processing of Yuanzhi was studied too.We concluded that there were 23 species of Polygala genus used as medicinal plants in China as well as 13 specjes and 2 variations used in Sichuan and Chongin through specimen and literature investigation. There were 11 species of Polygala genus used as ethnomedicine in 14 different minority region in China.The habit, zoologyical community as well as geographical and climatic characteristic of Yuanzhi were investigated and the nutrition eliments of soil was determined in this paper. Results explained that the sunlight and non-frost time of the year, content of available phosphor and moisture were the main impacts on the content of polygalic acid in Yunzhi. Therefore,the feasible cultivated place of Yuanzhi was plotted out according to the results above. All results can be a scientific reference for the good agriculture of Yuanzhi.For the first time DNA Molecular marker of RAPD and ISSR of P. tenuifolia Willd. and P. sibirica L.was studied in this paper and the PCR amplfying reaction system of Yuanzhi was established, Which will be reference for appraisement of germplasm of Polygala genus.In Chinese Pharmacopoeia (2005 edition, Vol. 1), the content of polygalic acid of Yuanzhi was the guideline related with the quality of Yuanzhi. In this paper, the quality of...
Keywords/Search Tags:Polygala tenuifolia Willd., P. sibirica L., Herbology, Soil, RAPD, ISSR HPLC, Processing, Pharmacology
PDF Full Text Request
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