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With Lung And Stomach Interrelated Theoretical Understanding The Cause And Pathogenesis Of Chronic Obstructive Pulmonary Disease

Posted on:2009-11-21Degree:DoctorType:Dissertation
Country:ChinaCandidate:D WangFull Text:PDF
GTID:1114360245450040Subject:Basic Theory of TCM
Abstract/Summary:PDF Full Text Request
Human lung and stomach is an important human viscera, and their physiological and pathological, there are many close ties. Fei Wei from the perspective of related chronic obstructive pulmonary disease pathogenesis, is the theoretical research in Chinese medicine practice on the part of the expansion, as the theory of Chinese medicine is the overall concept in the viscera of the correlation.BackgroundChinese medicine is a clinical disciplines, will study Chinese medicine theory and clinical integration, it is not only the "Huang Di Nei Jing" and other classics of Chinese medicine created the inevitable return is the classic Chinese medicine research. Visceral is the important concepts of Chinese medicine theory, the viscera of Chinese medicine is the re- lationship between the viscera of the core component of the theory, it not only embodies the Chinese medicine Wuzang and liufu, the official body obsessed connected inside and outside the overall concept, but also the guidance of clinical diagnosis and treatment medication. Viscera of the relationship between research, if only by yin and yang, the Five Elements, philosophy, history or math, and other abstract way to carry out theo- retical research, do not see it is the essence of the only combination of clinical, from the perspective of clinical research and analysis in order to draw reasonable Conclusion. Lung and stomach in the relevance of the theory of Chinese medicine in the proportion of viscera is not, related research reports and not many, but in clinical respiratory diseases in particular, chronic obstructive pulmonary disease (hereinafter referred to COPD), lung and stomach-related And runs through the disease has always been, in many of the viscera relations is particularly pro- minent, which deserves our relations on lung and stomach system to conduct in-depth study and exploration.At the same time, lung and stomach viscera with COPD for the study has a practical significance. Because of the increasing incidence of COPD is the increase in chronic airway disease, with the average human life extension and the ageing of the population trends of increasing signi- ficantly, COPD patients with the number, the recurrence rate is high and the high mortality rate, the treatment of difficult social and economic burden of re - , And other characteristics, has gradually become troubled many doctors and patients home the important public health problem. So far, COPD incidence mechanism has not yet entirely clear, awareness and prevention of COPD still have urgency and importance.PurposeBased on theory and clinical data analysis to specific organs lung and stomach on the relationship between the impact of specific diseases COPD as the starting point to explore Chinese medicine in the viscera of the overall clinical application. In theory right lung and stomach mutual relations in various aspects of the system; clinical starting to COPD in the statistical analysis on the basis of professional judgement, compr- ehensive analysis of clinical data on COPD syndrome, the symptoms of change, Mining lung and stomach focus viscera, lung and stomach preli- minary study in the relationship between the occurrence of COPD in the process of development. Application of the theory to guide lung and sto- mach Differential Treatment of COPD, to provide a theoretical basis; Related factors of a Logistic regression analysis.Methods1. Theoretical research: Ancient and Modern Literature in the summary and review on the basis of the lung and stomach in the anatomical structure, physiological function and pathological changes in the relationship betw- een COPD on the etiology and pathogenesis of Chinese medicine, Western medicine pathogenesis of research progress Literature Review.2. Clinical research: the clinical diagnosis of COPD clear standards of COPD in Chinese medicine clinical progress. Acquisition of 508 clinical cases of COPD, according to Fu whether gastric lesions in case symptoms divided into group 1 and group 2 patients, gender, age, personal history, past history, the sick time, the incidence season, the incidence incentives, the Chinese Permit conditions and the treatment of nine cases of group 1 and group 2 patients a comparative analysis, and 305 cases of a group of cases in accordance with the performance of gastric lesions Fu symptoms dialectical type; collected 508 of the 288 patients were hospitalized cases A retrospective survey, in accordance with the Group 1 and 2 patients in group divided into group 1 patients' group and the Case 2 ' group, in two patients during hospitalization and complications with regard to cases of a' group and the Case 2 ' Comparative Analysis of the group; collected 508 of the 220 cases of out-patient cases, groups the same way, whether by a stomach disease symptoms Fu divided into Group A and Case Case Group B, two patients with clinical signs and symptoms of seriousness of a comparative analysis.3. Statistical methods: SPSS10.0 medical statistics package, all of the data by computer to complete statistics, the measurement data measurement parameters to mean±standard deviation (X|-±S) said that the use of t-test and analysis of variance; count information With X~2 test.Results1. Case Group 1 and 2 cases of group: the gender composition of the two groups no significant difference (p>0.05), constitute its basic line, men high in the age composition of the two groups are significant differences (p <0.01), the average age of group 1 was significantly higher than the 2; two groups of individuals in the history of more significant difference (p<0.05). Among them, patients with a history of smoking accounted for 57 percent of patients with a history of alcohol accounted for 20 percent, preferred a diet with 12 per cent, live or work in a poor environment of 7 per cent; whether the two groups in the history of the past No differences were significant (p> 0. 05), a previous history of cases of the total number of cases of 94 percent, digestive, respiratory, kidney and urinary system diseases are caused stomach illness with symptoms of COPD risk factors; two groups of COPD The duration of illness on a significant difference (p<0.01), Case Group 1 Group 2 obvious cases of illness than the longer time; two seasons in the incidence of relatively no significant difference (p>0.05), are Winter and a high incidence of autumn; two groups of disease-induced factors, there were significant differences (p<0.05). Among them, cases of a group the incidence of eating incentives injured by 30 per cent, while cases of the two groups accounted for only 0.15 percent, a significantly higher than the two groups. Overall, the incidence of two cases of incentive descending order are: Shouliang flu (43.11 percent), restaurants injured (18.90%), to stimulate smell (15.16%), fatigue (11.22%), by the emotional trauma (6.89 percent), allergies (2.17 percent), other factors (2.36%). Clearly, Shouliang cold and diet COPD incidence is injured by the two major incentives; two groups of TCM more significant difference (p<0.05), in case a group, Tan Shi Yun-lung card of the group of all cases 45.28 percent, phlegm and blood stasis resistance of lung 36. 72%, while cases of two groups of Tan Shi Yun-lung of the Group of 39. 90 percent of all cases, phlegm and blood stasis resistance of lung 11. 82%, in this two-card, the group was a case Higher than the cases of two groups; comparative analysis of the two groups on the course, the length of a significant difference (P <0. 01), Case 1 treatment group than the obvious cases of the two groups to long on the prognosis of the situation the two groups, there was a significant Differences (P <0. 001), cases of a group of clinical cure rate was 28. 20 percent, compared with Case 2 Group 54.19%, Case 1 Case 2 was significantly better group of high cure rate; cases in accordance with a group of dialectical stomach Fu - Type of standards, certification of the difference between the percentage of larger, for the deficiency of 98. 69 percent, far higher than the 1.31 percent of the evidence. Stomach Qi Deficiency Syndrome cases of which the greatest number, accounting for 87. 21 percent.2. Case 1 ' group and the Case 2' group: two on the card and the occurrence of complications compared to a significant difference (P <0.01). Case 1 'group except for cerebral vascular disease, diabetes probability of no case 2' group, other complications and the probability of the occurrence of cases than 2 'group. One kidney and urinary system diseases in the Case 1 'group probability of the occurrence of 16.33%, while in case 2' group probability of the occurrence of 8. 70%, the Case 1 ' group was significantly higher than that of Case 2' group.3. Cases of group A and group B cases: in 19 clinical symptoms, in addition to dry mouth Yanzao, breathing shortness of breath, easy to cold, thin stool Tang, spontaneous perspiration, night sweats this six A, B were no significant conditions The difference (P> 0.05), the other 13 there are significant differences (P <0.05), which, in cough, sputum volume, short Buke mouth, insomnia, chills Zhileng this five, two Group's condition compared to a very significant difference (P <0.001), in Yaoxisuanruan and lower limb edema in the two groups of disease compared with the more significant differences (P <0.01). Generally speaking, A group of illness than the severity of Group B, A group of other diseases related to the viscera than in group B of high probability. In 11 clinical signs of, A, B compared to the two groups each of the indicators are significantly different (P <0. 05), which Shezhi, pulse and tongue fur the three signs of comparison, A, B groups have a very Significant difference (P <0.001). Can be seen from the table in Group A number of pathological signs higher than the frequency of Group B, Group A description of the group B in a serious condition. Group A and Group B from the clock comparison of the tongue, A group there is more Shezhi short, dark purple Shezhi, Qi and blood stasis is the resistance of the signs; tongue fur and more tired and less for Moss, no moss, Stomach Qi Tan Shi is the internal resistance and signs of weakness; more for the string slip pulse, weakness, Shen small lesions that more partial, biased true, Tanshi internal resistance even more serious.Conclusion1. In all 508 cases were attending a stomach illness symptoms were 305 cases, accounting for about 60 percent of the 203 cases, about 40%, the ratio of 1.5:1. Clearly, stomach and closely related to COPD.2. Incidence incentives, cold food cold and injured by the incidence of COPD the major factors that in the pathogenesis of COPD in the lung and stomach more relevance for the performance of the virtual Qi and lung or stomach problems, both inside and outside of evil, lung with gastric disease. In the card type, with a phlegm Yun-lung, Yuzu mainly lung. Clearly, the virtual COPD mainly for the performance of acute stage is relying on to the virtual subscript is mainly that of the present, to do more to lung and stomach wasting, and other viscera and-change. Sputum, blood stasis is a long course of COPD reasons, phlegm formed on the basis of phlegm and blood stasis guitar COPD is repeated attacks, the reasons for the increasing illness.3. Through Case 1 Case 2 and Group 1 and Group' group and the 2' group, the Fu found COPD gastric lesions in patients with symptoms of age more than getting sick quite a long time, many digestive history, as more than eating disease caused by injury, illness and more serious cases by the Group A and Group B cases, the discovery in the development and evolution of COPD in the lung and stomach related lung falling for more performance, lung and stomach with the disease, the spleen and stomach Chuan change, which many body organs involved, particularly involving the kidney. This is the crux of COPD can not be cured.
Keywords/Search Tags:Lung, Stomach, Chronic obstructive pulmonary disease, Relevance
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