The Intervenient Study Of Acupuncture And Massage Treatment On The Model Of Ovariectomized Rats

IntroductionWith the progress of human society,the development of science and technology,and gradually improved human health maintenance systems,the proportion of the elderly population increased significantly.According to the investigation of Shanghai Statistical Office,the life expectancy of Shanghai women has increased to an average age of 81.63.This means that most women can expect to live another third of their lives after menopause.Clearly, the health concerns of menopause-aged women are rapidly becoming a larger public health priority.Climacterium,a complicated biological process with versatile symptoms like:hot flashes,palpitation,night sweats,dizziness,insomnia, irritability,depression and memory recession,is associated with the gradual dying out of the hormonal activity of ovaries on the background of a general aging of the female organism.Menopausal transition usually began in 40s,the transition from female' s reproductive years to menopause,and the length of cycles will start to vary and begin to skip periods,the average age of the final menstrual period is around 50s.The worst situation of Climacteric syndrome sometimes will leads to the happening of Osteoporosis,Dysfunctional uterine bleed,Cardiovascular disease,Breast disease and Urology reproductive diseases.The Traditional Chinese Medicine(TCM) have long awareness of the Climacteric syndromes,in the early record of Nei Jing(Classics of Internal Medicine) already describes the syndromes,etiology and pathogenesis of Climacterium.After the Differential Diagnosis,the TCM recommend many treating methods including Medications,Acupuncture and Moxibustion,Massage, Cupping,Auricular points sticking and pressing,are all proved to be a safe and effective treatments.Menopausal symptoms vary in combination,intensity,and duration,and we assess the evidence for these as well.Estrogen,either by itself or with Progestins,has been the therapy of choice for decades for relieving menopause related symptoms.Epidemiologic studies in the 1980s and 1990s suggested that estrogen-containing therapy might protect women from heart disease and other serious medical problems.The Women' s Health Initiative(WHI) was a large clinical trial of postmenopausal women(age range,50 to 79 years[mean,63.2 years]) that was designed to see whether estrogen with or without progestin therapy could prevent chronic conditions,such as heart disease and dementia. The estrogen with progestin portion of the trial ended early because of increased incidence of breast cancer.There were increases in blood clots, stroke,and heart disease among women who received this treatment as well. These findings raised serious questions about the safety of estrogen to treat symptoms of menopause.Many women stopped hormone replacement therapy,and some searched for alternative therapies.As the result,the acupuncture and massage treatment of Traditional Chinese medicine has become one of the alternative options to seeking the cure of Climacteric syndromes.Except Hormone Replacement Treatment,there are many alternative remedies for Climacteric Symptoms;the use of Calcium,phosphorus,vitamin D supplementation are very important for prevention of Osteoporosis and Cardiovascular Heart Disease.Regular exercise benefits the heart and bones, helps regulate weight,and contributes to a sense of overall well-being and improvement in mood.the diet is an important tool that you can use to help control the menopausal symptoms.Reduce the amounts of caffeine in any foods, and carbonated beverages which contain phosphorous can prevent bone loss.The Traditional Chinese Medicine(TCM) had long awareness of the Climacteric syndromes,thought the descriptions of the syndromes are exist in the early record of Nei Jing(Classics of Internal Medicine),but the details of Climacterium are separately list in different name like "Menopause","Metrorrhagia","Bipolar disorder","Depression","Hot Flashes","Irregular Menstruation","Palpitation","Insomnia".Climacteric syndromes mainly caused by Kidney deficiency,kidney is the foundation of congenital essence,at the age of forty-night,sexual energy begins to decline, the Ren meridian becomes deficient,and the Chong meridian becomes scanty, deficiency of kidney yin weakens the kidney in its function of producing marrow, dominating bones and nourishing the brain,the result is dizziness,tinnitus, poor memory,soreness and weakness of the lumbar region and knee joints. Deficiency of yin produces endogenous heat,hence afternoon fever,malar flush, night sweating,dryness of the mouth,yellow urine and constipation, disturbance in the interior by heat of the deficiency type is the cause of nocturnal emission and insomnia.Another etiology and pathogenesis of Climacterium is spleen deficiency, spleen is the foundation of postnatal essence.Deficiency of the spleen implies inpairment of its function in transportation and transformation,which produces an insufficient source of Qi and blood,that explains pale complexion, lassitude,and dislike of speaking,weakness of the spleen qi indicates inability of the spleen to control blood,which leaks from the vessels and thus elicits purpura,bloody stools,excessive menstrual flow and uterine bleeding.Wansu Liu announce the theory "three stages of menstrual control" on his book Theory of Obstetric:adolescent women should pay attention to nourish the kidney,pregnant women should pay attention to manipulate the liver, menopausal women should pay attention to nourish the spleen,these theories has become the basis of climacteric syndrome treatment.After the Differential Diagnosis,the TCM recommend many treating methods including Medications,Acupuncture and Moxibustion,Massage,Cupping, Auricular points sticking and pressing,are all proved to be a safe and effective treatments.Many clinical and experimental researches show,to cure Climacteric syndromes with acupuncture can reaches the benefit of regulate the endocrine system,improve the microcirculation of nerve system,eliminate the inflammatory response of tissues,influence the neural pathways and neurotransmitters,adjust the immune system.Massage is one kind of the Chinese Medical treatments.With different ways of practices,it can stimulate the meridian of the body,improve the circulation of blood,and promote the metabolism,so as to cure the disease and strengthen the body,inhibits the process of aging.By using massage treatment,people can adjust the function of endocrine system and autonomic nervous system,and eliminate systemic or local symptoms.Objective Observed from the perspective of modern medicine,medical research has proven that there is a second brain in the body and it's located in the belly, the belly consists of more neurons than are contained in the entire spine. The abdominal autonomic nervous control the operation of visceral system,and sends signals to the brain by talking to a small number of "command neurons," which in turn send signals to the abdomen,control the circulation of qi and blood.Many symptoms of middle age women include Chest tightness,Tremor,palpitation,Rapid heart beat,headache,sweating,diarrhea,Constipation,Gastrointestinal discomfort,Urinary frequency are attribute to Abdominal endocrine disorders,through the treatment of abdominal massage will release these phenomena,and strengthen the regulation of central nervous system, achieve the effect of medical care.Many studies had shown acupuncture is an effective method to control climacteric syndromes,but seldom study focus on the effectiveness of combine acupuncture and massage therapies.In view of medical massage has the benefits of simple,cheap and efficacy,and considering both of acupuncture and massage have proved very effective for climacteric syndromes,combined acupuncture and massage therapy may be a reasonable option for patients.This study is to observe the effect of acupuncture and massage treatment on the model of ovariectomized rats,evaluate its effect of cure Climacteric syndromes,and explore its active mechanism.MethodTo established an animal experiment model for the indicator of Climacteric syndromes treatment.Fifty SPF grade rats were randomly divided into 5 groups-1 normal group and 4 model groups(remove ovarian),4 model groups are separately named control group,medicine group,massage group and acupuncture plus massage group,each group contains 10 rats.The normal group is only used for observation reference,the control group is used for treatment comparison,the medicine group is feed with artificial estrogen -Diethylstilbestrol. the massage group is treated with massage in the Abdomen and lower extremities acu-points twice a day,the acupuncture plus massage group is treated with acupuncture and massage at the same places as massage group.The ameliorative rates of syndromes before and after treatment was compared with physical and biological index including:weight,water intake,food intake, estrogen level(E),luteinizing hormone(LH) level,follicle stimulating hormone(FSH)level,Besides serum endocrine hormone,follicle stimulating hormone(FSH) and estradiol were determined before and after treatment in the study group.ResultsObserving model' s physical conditions of weight,food intake and water intake,and biological index of Estrogen level(E),Luteinizing hormone(LH) level,Follicle Stimulating Hormone(FSH) level and Gonadotropin Releasing Hormone(GnRH) level shows,the acupuncture and Massage have significantly effect in the treating of climacteric syndromes of ovariectomized rats.ConclusionCombined acupuncture and abdominal massage therapy on the treatment of Climacteric syndromes demonstrate many beneficial meaning,the first,it shows the traditional Chinese meridian has offer solid theoretical basis on Climacteric syndromes treatment,the second,it is the simple,effective and easy way to cure long-lasting refractory disease,the third,it reduces the cost of people' s medical expense.The advance of modern immunology and endocrinology knowledge help the medicine practitioners grasp the concept of treating chronic diseases like Climacteric syndrome with better insight,and learn how to adopt the philosophy of traditional Chinese medicine on "preventing the disease before get sick" and "strengthen the Physical power,dispel the pathogens" to maintain human health.Typical menopause symptoms such as hot flash or night sweat are caused by changing hormonal level in the female reproductive system.It is part of women nature self-healing process to deal with the change of their body due to aging.Based on these new knowledge and insight,most medical practitioners in major hospitals in the world do not treat climacteric syndrome as a serious disease that require heavy dose of medicine or intervention of surgery procedures;Instead most doctors now prescribe alternative medicine for menopause.Such as herbal medicine with compound that will produce progestational and estrogenic effects on humans and reduce the severeness of the syndrome.Other compound will increase body immune system which will help body heal itself and fight off the climacteric syndrome.In addition,some practitioners also discovered that acupuncture is another good alternative because the acupuncture has been shown to stimulate the immune system.It also has affects the circulation,blood pressure, rhythm and stroke volume of the heart,secretion of the gastric acid,and production of red and white cells.It also stimulates the release of a variety of hormones that help body to respond to injury and stress that cause by menopause.With this new knowledge,Traditional Chinese Medical treatments such as homeopathy and acupuncture become a new trend in modern medicine to fight climacteric syndrome.According to theory of traditional meridian,the study of abdominal cavity which contains the most organs in the body such as the digest tract,the liver and pancreas,the spleen the adrenal gland and the kidneys is not sufficient. This study of Chinese medicine is focus on physiological structure of the abdomen,it is an extensive and highly complicated structure that actually consists of more neurons than the brain,however,the deficiency of study abdominal anatomy is concerning.We should revelation of this study and hopefully will lead to more understanding of meridian mystery of abdomen with help from modern Anatomy,Electroneurophysiology,Endocrinology,and it will benefit significantly to the Traditional Chinese Medicine.