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Shenqi Pill Treatment Of Spleen & Kidney Yang-deficiency Type Of Experimental Study Of Peptic Ulcer

Posted on:2011-11-17Degree:DoctorType:Dissertation
Country:ChinaCandidate:Y Q LinFull Text:PDF
GTID:1114360305462905Subject:Diagnostics of Chinese Medicine
Abstract/Summary:PDF Full Text Request
Allergic rhinitis (allergic rhinitis, AR), also known as allergic rhinitis, is a common ENT diseases, is a common respiratory allergic diseases. The disease occurred in the nasal mucosa of allergic disease by nasal itching, sneezing, rhinorrhea clear tears, nasal swelling as the main features. In TCM theory and clinical studies, quantitative diagnostic study carried out a very important meaning:From the clinical point of view, TCM there is a certain degree of ambiguity, quantitative diagnostic methods can be more accurately grasp the dialectical standard, a more comprehensive and objectively grasp the patient's condition changes, improve the diagnostic level. From the perspective of traditional Chinese medicine research, due to traditional Chinese medicine theory and quantitative indicators that often exist in the clinical problem of insufficient use of quantitative diagnostic methods may increase the efficacy of new drugs, new therapies and other aspects of our assessment of objective-oriented, accuracy and results of the demonstration power contribute to the discovery of new problems, a breakthrough way of thinking. With regard to allergic rhinitis TCM Syndrome Research to quantify the problem, to date, based on epidemiological investigations, based on modern medical diagnosis based on Chinese medicine diagnosis of syndromes for the purpose of quantitative studies have not been seen. In our view, drawing on modern medicine, diseases, modern metrology and related mathematical statistical methods, based on the establishment of perennial allergic rhinitis reflects the common certificate-related projects TCM questionnaire, through the epidemiological investigation, using the method of mathematical statistics to find it is meaningful and valuable items and their common card type, in the diagnosis of been able to measure not only feasible, but also the research for perennial allergic rhinitis further research, prevention, treatment, and treatment evaluation of laying a solid foundation for The society has far-reaching practical significance. Objective: This study aimed to note that Interdiscipline play traditional Chinese medicine to its own advantages, using scientific methods to explore allergic rhinitis, the diagnosis of syndromes of traditional Chinese medicine model to allergic rhinitis population as the research object, using epidemiological methods, from the TCM waiting to start to carry out a certain sample size investigated. In this population symptoms, signs and other conduct statistical analysis of the frequency distribution of the population on the basis of traditional Chinese medicine syndromes in multiple ways mathematical statistics, quantitative research, diagnostic model or formula, and thus for the next allergic rhinitis TCM standardization, standardization of research provide the basis for, and to improve the accuracy of clinical medicine, in order to assess the clinical efficacy to perform their functions, that the combination of TCM Syndrome quantitative diagnostic reference inspiration.Methods:Set Perennial allergic rhinitis TCM questionnaire, questionnaire design reference and other documents. Limited to research time, the beginning of this study was intended to first study the allergic rhinitis the most common hot-Fan Fei Qi Deficiency and wind permit quantitative diagnosis, two disease syndromes contained in the levy incorporated, made the questionnaire. The research data will be collected into statistical data, creating databases, for each TCM scale initial diagnosis. Screened positive on the scale of the symptoms and signs such as the following data collation and analysis of:The symptoms of factor in the frequency control among the three groups to explore the relationship between symptom factors and permits. In each card, after filtering out common symptom factor, further analysis of whether these symptoms are related factors and permits in order to explore its clinical significance. This study, the symptom factors as elements of the study, the use of a case-control study aimed at balancing factors other than the study factor. OR value of symptoms in order to explore the link strength factor and permits. In exploring the symptom factors associated with the permit, based on the symptoms to further explore the link strength factor and permits in order to understand the symptoms factor in the diagnosis of cards. The introduction of odds ratio (OR value). OR value is a link strength index, is a point estimate study of factors used to assess the strength of the link with the card. OR values range from 0~+∞. When the OR value is "1, the study shows that there is a positive correlation factor and certificate, OR the value the greater the intensity of symptoms and the greater the contact card. According to OR values, the symptoms can be drawn strength factor and the size of the contact card sort in order to identify factors in the diagnosis of symptoms of significance. Data processing and analysis. Questionnaire on the recovery of a database with Epidata3.0 will input the data one by one check, not a unified project and check to correct the original questionnaire. Using EXCEL on the check and correct the data collation, classification. Two groups of 110 cases of survey data will be entered Mathlab data analysis software, using entropy-based partition of a complex system of data processing and analysis methods to extract the symptoms of allergic rhinitis factor information, summarized the basic card type, analysis, computation of the basic Syndrome Symptoms the contribution factor. According to the symptoms Fufen symptoms of 110 patients scoring to calculate the basic card types in the total symptom score, to enter data into SPSS statistical software, using diagnostic test in the ROC curve analysis method, reference points of different diagnostic sector, sensitivity and specificity to establish the diagnosis of various fundamental Syndromes threshold.Results:1. Through the frequency statistics law, the lung Qi-type perennial allergic rhinitis, the frequency of each symptom factor statistics, control and found that the frequency of each symptom factor is different:the nose itch:93.8%, sneezing:89.2%, stream-Qing tears:90.2%, nasal obstruction: 92.7%, Shenpi fatigue:86.4%, less gas lazy Introduction:84.7%, spontaneous perspiration:70.5%, cough, sputum White:68.1%. In which the highest incidence of nasal itching occurs. Through this study found that among the many symptoms, nasal itch factor in all the symptoms appear in the ratio is the highest, statistically explain the lung Qi-type perennial allergic rhinitis in nasal itching appears likely to be the greatest.2. Through the symptoms factor frequency statistics for wind-heat Fan Fei-type perennial symptoms of allergic rhinitis, the frequency of factors emerged statistics, control and found that the frequency of various symptoms of different factors: the nose itch:92.7%, sneezing:94.8%, nasal obstruction:91.6%, the evil wind fever:90.1%, headache and limb Chu:88.5%, nasal flow of yellow tears: 86.4%, thirst:69.3%. One sneeze occurs at the highest risk.3. In this study, the results section, we borrow OR values to illustrate the four symptoms of major research study on different factors in the differences. Two groups of subjects (Lung Qi Fan Fei-type wind heat type) symptoms of nasal congestion and nasal itch factor OR values were 1.19 and 1.16, indicating the occurrence of symptoms occurred in the two populations there is a difference in the probability, while sneezing and streaming tears of the symptoms of factor OR values were 0.45 and 0.98, indicating the occurrence of symptoms in the two groups in the incidence is no different.4. Is different from the symptoms of syndrome factors in accordance with its inherent laws of the organic combination of the different symptom factors cross-checks with different specificity designate the contribution, which is produced non-linear complex relationships between the symptom factors causes. In order to fully reflect the complex interactions between the symptoms, based on the complexity of the system partition entropy approach to symptom factors on the symptom factor collection (syndrome) in correlation, reflecting the contribution of a collection of symptoms to the degree of symptoms of lung deficiency is concerned, factors contribute to symptoms of the original order of degree of nasal itching, nasal congestion, runny nose, sneezing, Shenpi fatigue, less gas lazy statement, spontaneous perspiration, cough, phlegm white, right Qi has high diagnostic value of nasal itching, nasal congestion, runny nose, sneezing the contribution of other symptoms were significantly higher than the other symptoms consistent with clinical practice. Certificate of wind-heat Fanfei concerned, the original symptoms of Factor Contribution to sort of nasal itching, sneezing, runny nose, stuffy nose, bad wind or fever, headache and limb Chu, throat, thirst, for wind-heat Fanfei permit higher Diagnostic value of nasal itching, sneezing, runny nose, stuffy nose and other symptoms of the contribution degree were significantly higher than the other symptoms consistent with clinical practice.Conclusion:The results of analysis of complex systems based on entropy partition method can be achieved without supervision of TCM-related symptoms and symptoms of quantitative extraction operation, the results of their analysis than dealing with the multi-linear statistical methods more convincing. Entropy-based partition method of complex systems of perennial allergic rhinitis clinical data analysis showed that the basic syndrome (Qi Deficiency, wind-heat Fanfei certificate, etc.) test results with current literature and research findings understanding of basically the same. In this population symptoms, signs and other conduct statistical analysis of the frequency distribution of the population on the basis of traditional Chinese medicine syndromes in multiple ways mathematical statistics, quantitative research, card type diagnostic model or formula, which for the next allergic rhinitis TCM standardization, standardization of research provide the basis for, and to improve the accuracy of clinical medicine, in order to assess the clinical efficacy to perform their functions, that the combination of TCM Syndrome provide reference for the quantitative diagnosis of Enlightenment...
Keywords/Search Tags:allergic rhinitis, Chinese medicine, diagnosis, quantitative research
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