The Analysis Of Genetic And Epigenetic Stability In Aneuploid Of Common Wheat (CS)

Polyploidy and aneuploidy are common in plants,and represent numerical chromosome variations; As such, the two types of numerical chromosome changes have shared but also dramatically different genetic effects and biological consequences.Aneuploidy at both cellular and organismal levels is often linked to severely reduced fitness. Assuming that the aneuploidy-induced heritable changes of genes expression can be imparted to euploidy, then de novo genetic and/or heritable epigenetic changes must have been invoked.The aneuploidy wheat by E. R. Sears’ s classical work. were used to explore if epigenetic variations in the form of altered DNA methylation can be induced by the various types of aneuploidy; and if so, whether the newly acquired epigenetic modifications can be imparted to euploid progenies derived from the aneuploid mother plants.The results are:1. Aneuploid on wheat DNA composition change is minimal and genetic stability.2. Common wheat chromosome have extensive changes in DNA methylation patterns in the aneuploid and can stably inherited to the offspring。3. Aneuploid induced DNA methylation variable loci can evenly distributed in different wheat chromosome and no preference to any chromosome.4. Not only a large number of transposon like repeat sequences in Aneuploidy happened methylation changes mainly manifested as methylation reduced; but also of r DNA and cytochrome important protein influence,is an important source of variation of biological evolution.5.The changes of tmethylation patterns about aneuploidy is consistent of phenotype of wheat.At least certain types of aneuploidy in wheat appears to be a potent condition to generate heritable epigenetic variations in the form of altered DNA methylation patterns, and most of the induced epigenetic changes are heritable even if the aneuploidy was reverted back to euploidy. Our data have provided empirical evidence for earlier suggestions that heritability of aneuploidy-generated but aneuploidy-independent phenotypic variations may have an epigenetic basis. That at least one type of aneuploidy, i.e., monosomic 1A, was able to cause significant epigenetic divergence of the aneuploid plants and their euploid progenies also lends support to recent suggestions that aneuploidy may have played an important role inpolyploid genome evolution especially at initial stages of nascent polyploidization.