Reliability And Validity Of The Chinese Version Of The MBIS, I-QOL And UFS-HRQL In Patients With POP,Urinary Incontinence And Uterine Fibroid

Pelvic organ prolapse (POP), urinary incontinence (UI) and Uterine Fibroid(UF) are common non-fatal disease of the female reproductive system.Treatment for such diseases, in addition to anatomic reconstruction, the more important is to improve patient’s quality of life. Questionnaire as an assessment of patient-oriented approach is widely used in the POP, UI and UF clinical treatment and research. Many questionnaires currently used in pelvic floor and uterine fibroid research were validated in population of middle class Americans in American English. Most of them were validated in the target languages. As the conditions of domestic clinicians, most of the clinical used questionnaires were self-translated; this lacks psychometric cross-language translation and validation. It impedes the domestic clinical use of questionnaires and needs to be resolved.The validation of the Chinese version of the Modified Body Self-Image Scale (MBIS)ObjectiveTo evaluate the reliability and validity of the Chinese version of the Modified Body Self-Image Scale (MBIS) in patients with POP.Methods1. The Original English MBIS was translated into Chinese and linguistically validated following the Cross-cultural adaptation of health-related quality of life measures.2. Patients recruited randomly from PUMCH clinics were scheduled for two visits with2weeks apart, and they were surveyed through the Chinese version of the MBIS,SF-12and PISQ-12. 3. Evaluate the reliability and validity of the Chinese version of the Modified Body Self-Image Scale.ResultsA total of52POPpatients who met the criteria participated the study,All the subscales of MBIS showed high levels of internal consistency(Cranach’s α=0.926);moderate to excellent test-retest reliability(ICC:0.554-0.963,P<0.01)and acceptable construct validity. The MBIS and SF-12scores were negatively correlated.(r=-0.390;P<0.001). The MBIS scores and PISQ-12scores were negatively correlated.(r=-0.709; P<0.001).The validation of the Chinese version of Incontinence Quality of Life Questionnaire (I-QOL)ObjectiveTo evaluate the reliability and validity of the Chinese version of the Incontinence Quality of Life Questionnaire (I-QOL) in patients with UI.Methods1. The Original English I-QOL was translated into Chinese and linguistically validated following the Cross-cultural adaptation of health-related quality of life measures.2. Patients recruited randomly from PUMCH clinics were scheduled for two visits with2weeks apart,and they were surveyed through the Chinese version of the I-QOL,SF-12.All the patients have the1h pad test.3. Evaluate the reliability and validity of the Chinese version of the I-QOL.ResultsA total of148POP patients who met the criteria participated the study,within SUI47,UUI51, MUI50.All the subscales of I-QOL showed high levels of internal consistency(Cranach’s α=0.963); excellent test-retest reliability(ICC:0.74-0.96,P<0.01)and acceptable construct validity.The I-QOL and SF-12scores were positively correlated.(r=0.829;P<0.001). The I-QOLscores and1h pad results were negatively correlated.(r=-0.312; P<0.001). The validation of the Chinese version of The Uterine Fibroid Symptom and Health-Related Quality of Life (UFS-HRQL)ObjectiveTo evaluate the reliability and validity of the Chinese version of the The Uterine Fibroid Symptom and Health-Related Quality of Life, UFS-HRQL in patients with UF.Methods1. The Original English UFS-HRQL was translated into Chinese and linguistically validated following the Cross-cultural adaptation of health-related quality of life measures.2. Patients recruited randomly from PUMCH clinics were scheduled for two visits with2weeks apart,and they were surveyed through the Chinese version of the UFS-HRQL and SF-123. Evaluate the reliability and validity of the Chinese version of the UFS-HRQL.ResultsA total of190UF patients who met the criteria participated the study The Chinese UFS-HRQL had a high internal consistency (Cronbach’s alpha,0.912-0.976and high test-retest reliability (ICC coefficient,0.572-0.951; P<0.001).The symptom severity scores and SF-12scores were negatively correlated.(r=-0.813;P<0.001). The HRQL scores and SF-12scores were positively correlated.(r=0.620; P<0.001).The factor analysis showed good construct validity.ConclusionPsychometric testing supports the reliability and validity of the Chinese version of the MBIS, I-QOL and UFS-HRQL as an diease-specific measure of HRQOL.