The Research On Treating Stable Angina Pectoris And Mechanisms By Shaolin Qigong With Drugs

Objective:Appraises the effect of Qigong from Shaolin to patients who belonged to TCM syndrome of entangled phlegm and blood stasis with angina pectoris of effort and spontaneous angina pectoris, in order to explore the possible mechanisms of myocardial ischemia and collateral circulation establishing.Methods:Totally60cases of patients diagnosed coronary heart disease who met diagnostic criteria and inclusion criteria were randomly divided into Qigong group and control group with30for each. Qigong Group was given the treatment of Shaolinneigong combined drug therapy comparing with the control group treated by drug only. In the treatment of Qigong, patients trained for5days a week, twice a day,30seconds for sustained contraction and1minutes for pause between two contractions,3months continuously. Vital signs, type、extent and incidence of adverse event, angina pectoris, ECG,6-minute walk test, evaluation of FIM (functional independence movement), the measurements of EPCs (endothelial the progenitor of cells), VEGF(vascular endothelial growth factor), ET (peripheral blood endothelial prime), TXB2(peripheral blood thromboxane B2) and6-K-PGFla(6-keto-prostaglandin the F-la)were recorded before and after treatment to evaluate effect of Qigong from Shaolin to patients with unstability angina pectoris, ECG,6-minute walk test, FIM assessment,EPCs and VEG, and make correlation analysis between those indexes to explore the possible mechanisms of collateral circulation establishing.Results:1. Each group had non-significant differences on ages, sex, courses(P>0.05), can compare with each other.2.50cases (the Qigong group had24cases, the control group had26cases) had no adverse events during the treatment.3. There were significant differences on the overall effect, ECG,6-minute walk test, FIM assessment, EPCs and VEG between the two groups after the treatment.4. There is significant correlation among6-minute walk test, FIM assessment, EPCs,VEGand6-k-PGF la,what’s more, there is positively related among6-minute walk test, FIM assessment and EPCs.Conclusion:1.By comprehensive analysis of improvement of overall effect, ECG,6-minute walk test, FIM assessment,EPCs and VEG after the treatment, it confirmed that the Qigong from Shaolin which was safe and effective to the coronary heart disease and better than the control group(P<0.05)an effective way to reduce unstability angina pectoris’s attack, myocardial ischemia on ECG, improve patient’s ability of walking, FIM,EPCs and VEG to prevention and cure.2.EPCs is only and highly correlated with FIM and6-minute walk test which can increase number of EPCs to a certain extent, suggesting there is highly related between improving cardiac function and functional independence; There is significant correlation between EPCs and VEGF which is promoted secretion by angiogenesis in increasing collateral circulation and improving cardiac microenvironment.3.As the Qigong being a long-term movement approach used to health care in the treatment of ischemic heart disease like angina pectoris of effort and spontaneous angina,it made good use of the advantages of integrated tcm-wm to improve the cardiac function and the quality of life, raise treatment efficiency, integrate medicine resources effectively,add treatment target points, shorten patients’ length of stay and saved treatment cost.