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Comparative Analysis And Study On Clinical Indications Of Contrast-enhanced Ultrasound-guided Injections Of Hemostatic Agents As A Treatment For Abdomen Solid Visceral Trauma

Posted on:2014-07-24Degree:DoctorType:Dissertation
Country:ChinaCandidate:D WangFull Text:PDF
GTID:1264330425985853Subject:Oncology
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Purpose:1. Based on changes of every indicator of patients with abdomen solid visceral trauma (ASVT) before and after contrast-enhanced ultrasound-guided injections of hemostatic agents (HA treatment), to probe into patients’ recovery after such treatment and evaluate prognosis.2. By comparing changes of every indicator of ASVT patients receiving HA treatment with those receiving traditional surgery treatment, to discuss advantages of the former over the latter and evaluate the safety of HA treatment.3. To shed light on the indications and clinical experience of HA treatment for ASVT based on recent clinical practice.Methodologies:1. A comparison between the prognosis after HA treatment with that after traditional surgery treatment for ASVT:(1) Comparing ASVT patient indicators before and after HA treatment.(2) Comparing ASVT patient indicators after HA treatment with those after traditional surgery treatment.Comparative indicators are as follows:(1) Basic information and demographic data(2) Medical history and current conditions(3) Medical history record2. Discussion on indications and analysis of relevant techniques for HA treatment for ASVT:By analyzing the conditions of ASVT patients receiving HA treatment, probe into the indications of this therapy and relevant techniques.Results:1. A comparison between the prognosis after HA treatment with those after traditional surgery treatment for ASVT:(1) Comparing every indicator of ASVT patients before and after HA treatment. After analyzing main indicators, it can be found that:For the two sets of data of the HA treatment group before and after the treatment, the systolic blood pressure, respiratory rate, RBC, Hematocrit, hemoglobin, and glucose (P<0.05) have statistical significance. The pH, WBC, platelet, AST, Total bilirubin, direct bilirubin, carbamide, creatinine, PT and K+(P<0.01) have great statistical significance.(2) Comparing ASVT patient indicators after HA treatment with those after traditional surgery treatment. After analyzing main indicators, it can be found that:In terms of patients’ length of hospitalization, systolic blood pressure, Heart rate, respiratory rate, platelet, PT and Ca2+(P<0.05) have statistical significance. The hospitalization expenses, WBC, amylase, carbamide and APTT (P<0.01) have great statistical significance.(3) For the causes of all patients’injuries, traffic accident is the main factor followed by fall injury.Conclusion:1. Through a comparative study on the prognosis after HA treatment with that after traditional surgery treatment for ASVT, it’s found that:①Among patients with trauma, the occurrence in male is more frequent than female, and in aspects of age, young and middle-aged are predominant.②Traffic accident is the main reason for trauma.③After HA treatment for ASVT, the patients not only achieve the effect of hemostasis, but also are improved in all indicators including vital signs to some extent.④Compared with traditional surgery, HA treatment for ASVT is a therapeutic method easy for bedside operation with high benefit, and which not only achieves the expected results but also avoids organ removal.2. Discussion on indications and analysis of relevant techniques for HA treatment for ASVT:Its indications are concluded as follows based on clinical practice in recent years:(1) whether the patient suffers liver, spleen or kidney trauma and the trauma level; it’s recommended that HA treatment is adopted for the patient of Level-Ⅱ associated with active bleeding, Level-Ⅲ and Level-Ⅳ;(2) the age of patient is better at the range of18-55, and caution is required when a patient of older age is receiving treatment;(3) it’s better that the hemoglobin is more than70g/L, no primary disease of the blood;(6) the time from trauma occurrence to treatment shall not be too long, best within8hours. Except for late-onset viscera rupture.
Keywords/Search Tags:contrast-enhanced ultrasound, hemostatic agent, trauma, traditionalsurgery, minimally invasive surgery
PDF Full Text Request
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