A Clinical Research On The Treatment Of Traditional Chinese Medicine Combing With Western Medicine For Acute Stroke Complications

Objective:The purpose of this clinical study is settle a project which is confirmed by randomized controlled trial (RCT), multicenter observation,to treat the complications of the stroke in the acute phase. This project is connection the western medicine and the Rraditional Chinese Medicine,zhongfengxingnao oral liquid, which has been applied for more than20years.Method: The subjects of this study are from the inpatients departments of Affiliated Hospital of Chengdu University of Traditional Chinese Medicine,the People’s Hospital of Dujiangyan, Affiliated Hospital of North Sichuan Medical College, Panzhihua Hospital Integrative Medicine, the Affiliated Hospital of the the Guangyuan Hospital. There are210cases with lung infection and100cases of hemorrhagic infarction.The subjects are randomly diveded into two groups. Both groups were given the same treatments,the western medicine and the zhongfengxingnao oral liquid,however, the treatment group add the Chinese formulaes by nasogastric or ora50ml, tid, the course of14days.Observation period is3month, followed up and finished the origenal record and the CRF tables.Therapeutic efficacy: mortality,the number of days of hospitalization,lung infection syndrome,overall effcts,NIHSS score,(mRS) score, GCS score, life skills, and quality of life. will be observed to evaluate the effect of14days and28days,after treatment,and observe adverse reactions that may occur during the process of treatment. And use SPSS20.0analysis the data.Results:1Acute ischemic stroke with hemorrhagic infarction the phlegm heat Fushi patients resultsThere are25cases in both treatment group and in control group of the study of the acute phase of stroke and issude hemorrhagic infarction phlegm-heat Fu shi syndrome. The results are:the mortality of treat group is16.0%,in the control group is 24.0%,but there is no statistically significant difference between the two groups; After14days treatment and28days treatment,there is a statistically significant(p<0.05) of the data in the symptom score in signs points, GOS degree of disability, between two groups, what is more,the treatment group’s quality of life is better than the control group,and there is a statistically significant as well.(P<0.05).2Acute ischemic stroke patients with hemorrhagic infarction phlegm God permit resultsThere are25cases in both treatment group and in control group of the study of the Acute stroke patients with hemorrhagic infarction phlegm God permit results.The results are:the mortality of treat group is24.0%,in the control group is12.0%,but there is no statistically significant difference between the two groups;After14days treatment and28days treatment, there is a statistically significant(p<0.05) of the data in the symptom score in signs points, GOS degree of disability, between two groups, what is more.the treatment group’s quality of life is better than the control group.and there is a statistically significant as well.(P<0.05).3Acute stroke patients with pulmonary infection in patients with Phlegm obstruct the lungThere are53cases in treatment group and52cases in control group of the study of the Acute stroke patients with pulmonary infection in patients with Phlegm obstruct the lung syndrome..The results are:the mortality of treat group is11.5%,in the control group is18.9%,but there is no statistically significant difference between the two groups; After14days treatment and28days treatment,there is a statistically significant(p<0.05) of the data in the symptom score in signs points, GOS degree of disability, between two groups. After14days treatment, there is a statistically significant(p<0.05) of the data in GCS score,what is more.the treatment group’s quality of life is better than the control group.and there is a statistically significant as well.(P<0.05).4Acute stroke patients with pulmonary infection in patients with lung phlegm Yun resultsThere are53cases in treatment group and52cases in control group of the study of the Acute stroke patients with pulmonary infection in patients with lung phlegm Yun syndrome.The results are:the mortality of treat group is11.3%,in the control group is21.2%,but there is no statistically significant difference between the two groups; After14days treatment and28days treatment, there is a statistically significant(p<0.05) of the data in the symptom score in signs points,GOS degree of disability, between two groups. After14days treatment, there is a statistically significant(p<0.05) of the data in GCS score,what is more,the treatment group, s quality of life is better than the control group,and there is a statistically significant as well.(P<0.05).Conclusions:1The conclusion of acute ischemic stroke and complication of hemorrhagic infarctionThe number of days of hospitalization, hospitalization expenses,has been reduced in the treatment group,besides those,there are significant changes of the syndrome of acute stroke and complication of hemorrhagic infarction,in the treatment group,and the treatment group is better than the in control group,in the remarkable efficiency,total efficiency.2The conclusions of stroke in the acute phase and with the complication of pulmonary infectionThe number of days of hospitalization, hospitalization expenses,has been reduced in the treatment group,besides those,there are significant changes of the syndrome of acute stroke and complication of pulmonary infection,in the treatment group,and the treatment group is better than the in control group,in the remarkable efficiency,total efficiency.However,there is not obvious advantage of treatment group in reducing sputum culture positive rate and the percentage of neutrophils,and we need to expand the sample size for further study.