Study Of Treating Gastro-esophageal Reflux Disease With "Gallbladder Heatiness And Spleen Deficiency" Syndrome By "Gallbladder Cleansing And Spleen Replenishing" Method

Objective:By collecting the case about Gastro-esophageal Reflux Disease with "Gallbladder heatiness and Spleen Deficiency" syndrome in Malaysia,to observe the clinical curative effect of using"Gallbladder Cleansing and Spleen Replenishing" method,to explore the reasons why that Gastro-esophageal Reflux Disease with "Gallbladder heatiness and Spleen Deficiency" syndrome is more common in Malaysia,the etiology and pathogenesis of the disease,as well as the effectiveness of the application of "Gallbladder Cleansing and Spleen Replenishing" method to provide reference for the study and discussion of the clinical application of Malaysian Traditional Chinese Medicine.Method:A total of 72 cases of Gastro-esophageal Reflux Disease with "Gallbladder heatiness and Spleen Deficiency" syndrome were collected.According to the clinical symptoms of pantothenic acid,heartburn,post-sternal pain or discomfort,belching or reflux symptoms in RDQ questionnaire,combined with other anti-flow secondary symptoms integrals,before and after treatment,by modified Chaihu Guizhi Ganjiang decoction with three courses of treatment,four weeks is a course of treatment,a total of 12 weeks,a decoction per day by twice,the observation points are before treatment,1st(4 weeks),2nd(8weeks)and 3rd(12weeks)course of treatment,after three courses of treatment(12weeks),evaluation of clinical efficacy.After end of treatment,stop the medication for 3 month of follow-up to observe long-term effects.Result:In this observation after 72 cases were studied,the patients with duration of the disease who were over 1 year was the most,the number of patients between the aged of 21 and 40 was the most too,followed by 41-60 patients,it mention that the majority patient are young and middle-aged people,and the most common factors are dietary factors and no obvious inducement,which is related to unhealthy addictions and eating habits and so on.Before the treatment,the main symptoms of "Gallbladder heatiness and Spleen Deficiency" syndrome include pantothenic acid,heartburn,post-sternal pain or discomfort,belching or nausea,sore throat,dry mouth,hunger pangs,epigastric pain,fatigue,insomnia,etc.The result after clinical treatment to the 72 cases,18 cases of clinical recovery(25%),27 cases of significant effective(37.5%),16 cases of effective(22.22%),11 cases of invalid(15.28%),the total effective rate was 84.7%.The main symptoms pantothenic acid,heartbum,post-sternal pain or discomfort,belching or nausea and other secondary symptoms were significantly decreased after treatment,and the difference was statistically significant(p<0.05).Observation of long-term efficacy after drug withdrawal,but in 61 effective cases,more than half of them lost contact,missing judgment recurrence rate and long-term efficacy index,this had to do with local conditions.Conclusion:The reason for the common Gastro-esophageal Reflux Disease with "Gallbladder heatiness and Spleen Deficiency" syndrome in Malaysia,it is 'believed that there is a great relationship "with the unhealthy lifestyle factors,in addition,the patient has a long delay in the relative course of illness,it may cause the deficiency of spleen and stomach turn to excess syndrome by deficiency,it leads to the delay of the illness.After observing the clinical efficacy by apply "Gallbladder Cleansing and Spleen Replenishing" method,the clinical efficacy get a good overall efficiency,it's a efficiency treatment for patient in Malaysia,only currently lack of long-term efficacy observation,therefore,further research is needed.