Objective: By observing the clinical effect of spleen dampness decoction(spleen dampness type)to the treatment of Gastro Esophageal Reflux Disease therefore,to get comprehensive evaluations from the aspects the improvement of the accumulating points of TCM symptom,clinical safety as well as the incidence and recurrence rate of the adverse reactions,then to get the primary assessment of clinical therapeutic effectiveness,so that to provide experimental evidence for the treatment of diarrhea predominant irritable syndrome.Methods:the control group received treatment by Omeprazole enteric capsules,20 mg,1 times a day.And the treatment group received treatment on the basis of the controlled group and add the spleen dampness decoction provided by the second Luoyang Hospital of traditional Chinese medicine in pharmacy.It unified fried by the Institute of medicine decocting machine,one dose a day,morning and evening hours services;Two groups were treated for four weeks.In order to compare the long term effect of two groups,afterwards each patient in two groups was questioned about past treatment for 3 months at the end of treatment.In order to compare the recurrence rate condition of two groups,afterwards each patient in two groups was observed and recorded about the treatment before and after 3 months in clinical symptoms,aspects and other signs of change.Results:Clinical observation showed: firstly,the study included 64 cases,fall off in 4 cases.There are 30 cases in the treatment group,while 30 cases in the control group after testing.The results of statistic analysis showed that the two groups before treatment have no obvious differences in age,gender,disease duration(P > 0.05),So,it is comparable;secondly,the comparison of 2 traditional Chinese Medicine curative effect: the total efficiency of 90% treatment group was much better than the controlled group because its total efficiency is about 76.67%,there are significant statistical differences in the efficacy of the two groups(P < 0.05),which showed that the spleen dampness Decoction in the treatment of gastro esophageal reflux disease(spleen dampness type)in patients with clinical efficacy is significantly better than Omeprazole enteric capsules.Thirdly,The effects of 2 treatment group in improving patients eructation,acid regurgitation,area pain,abdominal fullness,fatigue,loss of appetite and other aspects of the superior to the control group.Fourthly,afterwards each patient in two groups was questioned about past treatment for 3 months at the end of treatment.The recurrence rate of the treatment group was significantly lower than the control group,and it showed that the spleen dampness decoction has more advantages in the long-term curative effect.Conclusion:Compared with the western medicine in improving the clinical symptoms of patients,spleen dampness decoction for the treatment of(spleen dampness type)of Gastro Esophageal Reflux Disease has better curative effect.What significantly reduces the recurrence rate with no obvious damage of liver and renal during treatment,and can relieve the economic burden of the patients,worth clinical promotion. |