Font Size: a A A

Thymosin alpha(1) antagonizes induced apoptosis of thymocytes: A model to study the molecular mechanism of thymosin alpha(1) action

Posted on:1998-08-16Degree:Ph.DType:Dissertation
University:The George Washington UniversityCandidate:Baumann, Christian AndrewFull Text:PDF
GTID:1464390014978236Subject:Biology
Abstract/Summary:
poptosis of thymocytes is a crucial process in the development of T cell mediated immunity. It is well established that glucocorticoid hormones and anti-CD3 monoclonal antibodies induce thymocyte apoptosis. This process can be modulated by growth factors, antioxidants, and adhesion receptors. To investigate the effect of thymic hormones in modulating thymocyte apoptosis, this study examined the effect of thymosin...
Keywords/Search Tags:Thymosin, Apoptosis
Related items