| Prescription compatibility is an essential link in the process of clinical prescription preparation.As one of the important compatibility forms of prescriptions,sexual flavor compatibility is the most characteristic part of the theory of traditional Chinese medicine.The study of sexual flavor compatibility is not only helpful to guide the clinical prescription preparation,but also of great significance to inherit the theory of traditional Chinese Medicine.In combing the development context of ancient doctors’ application of the theory of nature and flavor to send medicine and make prescriptions,it is found that Wu Jutong’s application of the theory of nature and flavor compatibility is very characteristic,especially in the treatment of damp heat febrile diseases.Objective:Taking nature and flavor as the framework and Sanjiao syndrome differentiation as the program,To study the specific application of the compatibility method of nature and flavor of prescriptions for the treatment of damp heat febrile diseases in the WenBingTiaoBian,explores the regular of nature and flavor compatibility in the treatment of damp heat and febrile diseases,better understands the purpose of its composition,and provides reference and reference for the preparation of prescriptions for the clinical treatment of damp heat diseases.Research methods and contents:This research adopts the methods of literature mining and theoretical research.Firstly,the development context of ancient doctors’ application of nature and flavor theory to send drugs and make prescriptions was systematically analyzed;it systematically combs the development context of ancient doctors’ application of nature and flavor theory to send drugs and make prescriptions;On the basis of understanding the theory of treating damp-heat febrile diseases by mechanism and syndrome in WenBingTiaoBian;Taking the theory of nature and flavor as the framework and the differentiation and treatment of Sanjiao as the program,through screening,sorting and analyzing the compatibility methods of nature and flavor of prescriptions used in the development of damp heat febrile diseases in the WenBingTiaoBian and their relationship with pathogenesis and treatment,Comprehensively summarize the idea of compatibility of nature and flavor of prescriptions used in the treatment of damp heat febrile diseases in WenBingTiaoBian;Through the analysis of representative formula of its common compatibility methods of nature and flavor,this paper studies the inheritance and development of Wu Jutong’s previous thought of compatibility of nature and flavor in the treatment of damp heat febrile diseases.Result:One:Historical evolution of compatibility of nature and flavor of ancient prescriptionsLiterature mining method is used to systematically comb the historical origin of the application nature and flavor theory of ancient doctors to dispatch prescription.Through analysis,it is found that the development of the compatibility of nature and flavor in ancient times can be divided into five stages.In the pre Qin period,the ancients’ understanding of the compatibility of nature and flavor was still in the embryonic stage;In the Han Dynasty,the HuangDiNeiJing,ShenNongBenCaoJing,ShangHanZaBingLun and other works came out,which became the foundation stage for the development of the theory of compatibility between nature and flavor;In the WeiJinSouthern and Northern Dynasties,the theory of compatibility of nature and flavor was in a slow development stage;During the Jin and Yuan Dynasties,physicians explained the theory of compatibility of nature and flavor in their works,which enriched and developed the theory of compatibility of nature and flavor.The four great masters of the Jin and Yuan Dynasties represented physicians;In the Ming and Qing Dynasties,the understanding and application of the theory of compatibility of nature and flavor reached its peak.The theory of compatibility of nature and flavor has been constantly improved and expanded through the play of various doctors.Among them,Wu Jutong’s inheritance and application of the theory of compatibility of nature and flavor has made great progress in the research of dispensing prescriptions,his thought of compatibility of nature and flavor is worthy of our in-depth study.Two:Study on syndrome differentiation and treatment of damp heat febrile diseases in WenBingTiaoBianThis study analyzes and summarizes the pathogenesis and syndrome treatment of damp-heat febrile diseases by means of theoretical research.Damp heat febrile diseases in WenBingTiaoBian include summer heat,damp heat,summer heat,malaria,dysentery,jaundice and arthralgia,Wu Jutong believes that this disease is due to "the inability to transport the moisture of water and valley inside and the complex feeling of seasonal moisture outside",The pathogenesis is accumulation of damp and heat,block of Qi mechanism,diffuse Sanjiao,trapping Yang and injuring Yin;It is characterized by aversion to cold and fever,low heat potential,severe head and body pain and gastrointestinal symptoms,The location of the disease is centered on the Spleen and Stomach,and all Threejiao systems are affected;Because the dampness evil is heavy,muddy and greasy,the transmission time is long,the disease is lingering,and the course of disease is long;Wu Jutong regards the differentiation of Sanjiao as the differentiation program of damp heat disease,this paper explains the pathogenic characteristics,transmission and transformation ways,transmission and transformation regulars,syndrome characteristics and treatment principles of damp heat evil gas through Sanjiao syndrome differentiation,and its prognosis is different from transforming dryness and damaging Yin and Cold;Various syndrome differentiation.Three:Compatibility Guiding ideology,principles,methods and characteristics of compatibility of nature and flavor of prescriptions for the treatment of damp heat febrile diseases in WenBingTiaoBianThis part takes the prescriptions for the treatment of damp heat febrile diseases in the WenBingTiaoBian as the research object,classifies them according to the Sanjiao and the transformation of dryness and injury of Yin and Cold in the later stage of the disease,and reorganizes and analyzes the compatibility methods of nature and flavor of the prescriptions for the treatment of damp heat febrile diseases in combination with the pathogenesis and treatment methods.Inclusion criteria:This study was included in accordance with the prescriptions in the articles related to damp heat febrile diseases in the WenBingTiaoBian,among them,including the pathological stages of dryness,Yin injury and Cold in the pathogenesis of damp heat febrile diseases.Note:the development process of damp heat febrile diseases is a continuous and dynamic process.In the process of its development,it can not only feel the different proportion of damp evil and heat evil,but also change dryness,injure Yin and Cold.Moreover,Wu Jutong also mentioned this pathological stage of damp heat febrile diseases in the WenBingTiaoBian.Therefore,this study included them into the study,so as to comprehensively sort out To analyze the compatibility characteristics of nature and flavor of prescriptions related to the treatment of damp heat febrile diseases in the WenBingTiaoBian.Exclusion criteria:(1)According to the content of the article,the relevant prescriptions for pure deficiency syndrome in the later stage of disease development;(2)Wu Jutong indicated in the text that he should be included in the cold and dampness..Results:Through summarizing,it was found that the compatibility methods of nature and flavor used in the treatment of damp heat febrile diseases include 13 compatibility methods,such as XinWen method,XinLiang method,XinDan method,KuXin method,KuWen method,KuHan method,DanShen method,GanDan method,SuanGan method,GanKu method,SuanKu method,XianHan method and SuanWen method.The nature and flavor of compatibility method adopted by Wu Jutong in the whole development process of the treatment of damp heat febrile diseases constitutes the nature and flavor of compatibility system for the treatment of damp heat febrile diseases in the WenBingTiaoBian.Four:The train of thought of compatibility of nature and flavor of prescriptions for treating damp heat febrile diseases in WenBingTiaoBianThis part mainly arranges and summarizes the theoretical basis,program,key treatment methods and characteristics of the compatibility of nature and flavor of prescriptions for the treatment of damp heat febrile diseases in the WenBingTiaoBian.1 Theoretical basis of compatibility of nature and flavor in prescriptions for treating damp heat and febrile diseases--Six Qi wins recoveryLiu Qi Sheng Fu combines the Five Elements theory with the five flavors of medicine and the theory of Zang Xiang.With the compatibility of drug nature and flavor as the core,the compatibility of drug nature and flavor provides theoretical guidance for treatment of different evil Qi,and becomes the basis for the application of the theory of drug nature and flavor in the treatment of diseases in Traditional Chinese Medicine.Wu Jutong’s application of compatibility of nature and flavor in the treatment of damp heat febrile diseases also originates from this,but it is not completely copied.In the treatment of damp heat,it is based on the guidance of Liu Qi Sheng Fu,According to the specific pathogenic characteristics,pathogenesis and location of the disease,we can flexibly choose the drugs with corresponding flavor to adjust the imbalance between Yin and Yang,Five Elements,Viscera and Qi and Blood,so as to achieve the purpose of eliminating pathogenic factors and calming diseases.2 Principle of differentiation and treatment of compatibility betw een nature and flavor of prescriptions for treating damp heat febrile diseases--differentiation and treatment of SanjiaoThe analysis shows that Wu Jutong also embodies the differentiation and treatment of Sanjiao in the application of compatibility of nature and flavor.Heat and dampness in the Shangjiao,or aromatization with XinWen method or clearing with XinLiang method;for those with Lung qi disharmony,they should make good use of "slightly KuXin method to promote Lung qi",Or combined with DanShen ventilation.The medication emphasizes light quality,small quantity,Xin flavor and thin nature,which reflects the principle of "treating Shangjiao like a feather,not lifting it if it is not light";The key to the treatment of damp heat in the Zhongjiao is to restore the Qi lifting mechanism of the Spleen and Stomach of the Zhongjiao.The KuXin method,one rising and one falling,conforms to the physiological characteristics of the Spleen and Stomach.The Xin flavor is appropriate to remove the Spleen dampness,and the Ku flavor is appropriate to clear the Stomach heat,which embodies the principle of "treating the Zhongjiao as a balance,not as a peace";The disease in the Xiajiao.Make good use of the situation.Under the premise of ventilating the ventilator,it is particularly suitable to dilute infiltration and diuresis.Therefore,the common compatibility method of nature and flavor is KuXindan method;3 The key treatment of compatibility of nature and flavor of prescriptions for the treatment of damp heat febrile diseases--Regulating QiSanjiao is the running channel of human Yang and water.Sanjiao gasification summarizes the gasification function of human viscera.Damp heat has the characteristics of diffuse Sanjiao.Therefore,the most typical feature of damp heat disease is the disorder of human Sanjiao metabolism.Therefore,it is the key to restore the gasification function of Sanjiao.Therefore,Wu Jutong runs through the nature and flavor of compatibility method of herbal medicines of KuXinxuantong in the treatment of damp heat febrile diseases,in which he pays particular attention to dispersing Lung Qi to regulate the Qi of Sanjiao and smooth the Qi of Zhongjiao.4 Compatibility characteristics of nature and flavor of prescriptions for treating damp heat and febrile diseases--distinguishing damp heat and disease stage4.1 The method of distinguishing the specific gravity of humidity and heat and determining the compatibility of nature and flavor:Affected by factors such as evil Qi and constitution,in the process of the development of damp heat disease,the proportion of the two evil Qi of damp heat is different,and the specific application of the method of compatibility of nature and flavor is also different.For those whose humidity is heavier than heat,the Shangjiao is mainly XinWen method,the Zhongjiao is mainly KuXinwen method,and the Xiajiao is mainly KuXindan method;For those with severe damp and heat,and the Zhongjiao is mainly KuXinhan method,and the Xiajiao is mainly KuXindan method.Heat is more important than dampness,and the Zhongjiao and Xiajiao are mainly KuXinhan method,the Shangjiao is mainly XinLiang method;4.2 Method of nature and flavor of compatibility in disease stage:Damp heat febrile diseases in the early stage and middle stages,evil is the main thing,The commonly used method of compatibility of nature and flavor is mainly KuXin method;In the late stage of damp heat febrile diseases,Wu Jutong advocated the use of GanHan method and KuHan method to nourish and strengthen Yin,consolidate and nourish Yin fluid;Those who become Cold in the later stage of damp heat febrile diseases,Wu Jutong advocated the method of KuXinwen and warm to dispel dampness and disperse cold.5 Common properties,nature and flavor of compatibility methods and medication characteristics of prescriptions for the treatment of damp heat febrile diseases5.1 Common compatibility methods:(1)Make good use of KuXin method:the KuXin method is the most commonly used method for the treatment of damp heat febrile diseases,According to the location of the disease,the proportion of damp heat,pathogenesis,treatment and other factors,specific applications include KuXinhan method,KuXinwen method,KuXindan method,KuXintong method;(2)Skillfully use XinWen method and KuWen methods:Dampness is an evil of Yin,which cannot be cured by Wen,so it is appropriate for dampness to cause disease and be cured by Wen;Pungent herbal medicine,which can work and disperse;Bitter herbs can relieve and dry;Wu Jutong linked the effects of bitterness and bitterness with the characteristics of damp heat pathogenesis,In the differentiation and treatment of damp heat febrile diseases,the methods of XinWen and KuWen are skillfully used.5.2 Herbs characteristics:(1)Suan herbs:for those with damp heat accompanied by Jueyin liver heat,the KuXinhan method is combined with Suan herbs,such as BaiShao;(2)KuHan herbs:the product of KuHan herbs(such as HuangLian)is a herbs for walking inside.Evil invades Shanjiao and does not reach the Zhongjiao,so it should not be used;(3)XinWen aromatics herbs:(1)aromatics can dispel exterior evil;(2)Aromatization of dampness and invigorating the Spleen;(3)Fragrant,soothing and opening Collaterals.6 Clinical medication of Wu Jutong in the treatment of damp heat disease6.1 The herbs nature and flavor under the guidance of disease location identification:(1)The disease lies in the Shangjiao:the heat evil is biased,and there are both dampness evil:the herbs of XinLiang is better,such as JinYinhua LianQiao;Dampness evil focuses on those with heat evil,and it is appropriate to turn Xin Xuanfanghua,such as "XiangRu,Huoxiang";The specific compatibility methods are different according to the pathogenesis,the proportion of damp heat and the treatment methods,The Lung loses its vitality,For example,KuWen’s XingRen almonds with XinLiang’s JinYinhua and LianQiao;If urination is unfavorable,it can be combined with HuaShi and YiYiren seed to relieve dampness.In addition,the selected drugs should be light in weight,small in quantity,thin in flavor and Liang in nature.Those who have not committed the Zhongjiao should not use KuHan sedimentation products;(2)The disease is in the Zhongjiao,the method of treating KuXin method is appropriate,The herbs of KuHan often uses HuangLian HuangQin and ZhiZi;ZhiShi,HouPo,CangZhu and ChenPi are often used as KuXinwen herbs;BanXia,HouPo and ShengJiang are often used as XinWen herbs;FuLing,ZhuLing and HuaShi are often used as the herbs for Light permeability and diuresis herbs;(3)The disease is in the Xiajiao,and it is appropriate to be KuXindan methods.KuXinwen herbal medicine often choose HouPo,DaFupi,CangZaojia and CanShan,etc.and KuHan herbal medicine often choose ZhiZi,MuTong and ZhuYe,etc;FuLing,ZhuL ing,TongCao and YiYiren are often used as light permeability and diuresis herbs.6.2 Herbs of nature and flavor under the guidance of distinguishing the proportion of damp and heat:when the clinical prescription is dispatched,combination with the characteristics of disease location and pathogenesis.If the heat is heavier than dampness,when the clinical prescription is condemned,it is advisable to increase the flavor or dosage of KuHan herbs and reduce the flavor or dosage of XinWen herbs;6.3 Advantage of the situationIdentify disease stage:(1)In the early and middle stages of damp heat,mainly based on evidence,and the method of treating bitterness and bitterness;In the later stage of the disease,according to the different pathogenesis and disease location,the herbs used to nourish Yin are classified as follows:1)GanHan method:MaiDong and ShaShen,etc.2)GanKu method:GanHan herbal medicine as MaiDongand ShaShen compatible with KuHan herbal medicine as HuangLian and HuangQin;3)SuanGan method:Sour herbal medicine as WuMei and BaiShao compatible with GanWen herbal medicine asAJiao and GanCao,etc.4)XianHan method:MuLi and XiJiao;5)SuanKu method:Suan herbs BaiShao and WuMei are combined with KuHan herbs HuangLiang and HuangQin;In the later stage of the disease,the herbal medicines used to warm Yang are classified as follows:(1)warm SpleenYang method:RenShen and GanJiang;(2)warm ShenYang:FuZi,XiXin,GuiZhi,etc;(3)Tongyang method:FuLing.In addition,when dispensing drugs in clinical prescriptions,first,we should give consideration to the Sanjiao,because damp heat is easy to diffuse the Sanjiao;Second,we should strengthen the Spleen and awaken the Stomach,If the spleen and stomac h are in disorder,the dampness evil is not easy to be eliminated;Third,we should r egulate Qi,if Qi is not enough,water is not available.Five:Wu Jutong’s inheritance and innovation of KuXin method of XieXin DecoctionThis part mainly takes XieXin Decoction as the research object,By analyzing how Wu Jutong applied the method of nature and flavor of compatibility in clinical practice,this paper innovated the addition and subtraction of XieXin Decoction.1 The study found that Wu Jutong was based on the HuangDiNeiJing and Zhongjing,Further inherit and develop Ye Tianshi’s application of KuXin method,Under the guidance of Sanjiao syndrome differentiation program,a series of KuXin method prescriptions for the treatment of damp heat febrile diseases were summarized in the WenBingTiaoBian,It has greatly enriched and developed the application of Kuxin method in damp heat febrile diseases..2 Wu Jutong believes that Ye Tianshi’s LinZhengZhiNanYiAn is one of the medical classics that can be followed.He has carefully studied Ye Tianshi’s clinical evidence prescription,deeply understood and understood Ye Tianshi’s basic idea of changing the general and prescriptive prescriptions through the compatibility of nature and flavor,summarized it in the treatise on febrile diseases,listed it in articles,titled it with the name of the prescription,and explained the regular of compatibility of nature and flavor,which not only preserved and inherited Ye Tianshi’s thought of compatibility of nature and flavor,but also,So that future generations can better learn and understand the idea of the compatibility of nature and flavor in legislation3 Research findings the theory of nature and flavor of compatibility in HuangDi NeiJing is the theoretical basis of Wu Jutong’s prescription;The classic prescriptions in ShanHanZaBingLun is the practical basis of Wu Jutong’s application of nature and flavor in dispensing medicine;Ye Tianshi’s thought of abiding by the regular and changing prescriptions is the guiding ideology of Wu Jutong’s application of compatibility of nature and flavor in dispensing prescriptions.At the same time,the compatibility of nature and flavor of prescriptions is not only the core of inheriting prescriptions and syndrome differentiation,but also an important way to inherit and innovate classical prescriptions.Conclusion:Through systematic research,it is proposed that the idea of the compatibility of nature and flavor of Wu Jutong’s prescriptions for the treatment of damp heat like febrile diseases is based on the theory of "Six Qi Wins Complex" and the principle of differentiation and treatment of Sanjiao;The key treatment method is to promote Qi circulation;It is characterized by differentiation of damp heat and disease stage;To make good use of the KuXin method,the application of the KuXin method is more inclined to the KuXinhan method.BanXia of XinWen and HuangLian of KuHan are the core drug combinations for its application of the method of "Xin opening and Ku descending";Skillfully use XinWen method and KuWen method.Wu Jutong’s application of the method of compatibility of nature and flavor to make prescriptions and prescriptions was deeply influenced by the HuangDiNeiJing,Zhang Zhongjing and Ye Tianshi.His application of the theory of compatibility of nature and flavor to make prescriptions can be traced back,inherited,developed and innovated. |