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Researches On Applications Of Near Infrared Spectroscopy In Traditional Chinese Medicine

Posted on:2004-11-04Degree:MasterType:Thesis
Country:ChinaCandidate:G L HuFull Text:PDF
GTID:2121360092481270Subject:Biochemical Engineering
Abstract/Summary:PDF Full Text Request
Traditional Chinese Medicine (TCM) is a great treasure of China, while TCM is facing serious problems to become a kind of modern medicine accepted by the world. Those mature technologies in other areas should be used into TCM to settle these problems. Near Infrared Spectroscopy (NIRS) is a kind of successful technology which is widely used in lots of areas, such as agriculture, food industry and petrochemical engineering. The applications of NIRS in TCM are studied in this paper.The quality of TCM is directly due to the quality of TCM materials, while there is not a kind of modern instrumental analysis method to judge the quality of TCM materials, so we have to judge the quality of TCM materials by experienced workers. In this paper, a news method to classify the quality of TCM materials based on NIRS is reported. By digitalization of the qualitative results of Man-made Quality Judgment and correlation with NIRS data, a model can be established with calibration of this method to the Brassica Campestris pollen is made. The prediction veracity is 92.3%. This result shows that the classify method of TCM materials based on NIRS is viable with good catholicity.Instant analysis by NIRS in TCM process is discussed in this paper. The total flavones and total lactones in Gingko Biloba Extraction (GEB) liquor are determined by NIRS with Partial Least Square (PLS). The multicorrelation coefficients of the model to the total flavones and total lactones of the prediction samples are 0.985 and 0.971, the RSD are 2.44% and 3.19%. The result shows that the method proposed can be used to simultaneously analyze the total flavones and total lactones in GEB liquor with high accuracy under strong absorption of menstruum, and the application of NIRS in TCM process to the area of instant analysis and on-line control is possible.These are a lot of samples in TCM are powder, concentrate and atactic solid. Such kinds of samples cannot be directly analyzed by normal analysis method. In this paper, the total flavones in GEB powder directly determined by NIRS is studied. The multicorrelation coefficients of the prediction samples are 0.973, the RSD is 1.13%.inThis result shows that NIRS can be used to directly determine the TCM with high speed and good veracity.In a word, the application of NIRS in TCM has a good potential and it will help to settle some problems in the modernization of TCM. But the research of NIRS' application in TCM is still in laboratory and a lot of researches should to be done to realize the application of NIRS in TCM industry.
Keywords/Search Tags:Near infrared spectroscopy (NIRS), Quality classify, powder, Traditional Chinese Medicine (TCM), TCM materials, instant analysis, Brassica Campestris, Gingko Biloba Extraction (GEB)
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