Kinetics Of Pt(IV) Compound Oxide AminopHenol And Study On Analyse GA₃,IAA By HPLC

The development of platinum anticancer grugs since 1965 and the development of analyse plant incretion by HPLC were reviewed in this paper. The kinetics and mechanism of oxidation of L- cysteine and L- cysteine hydrochloride by Na₂PtCl₆ has been studied in aqueous medium by convertional spectrophotometry. In the temperature range of 25 - 32 °C , through analyzing influences of [H⁺] and [L- cysteine]_tot on the reaction, it is pseudo-first-order in Pt(IV) disappearance with an rate expression: Activationparameters associated with k_obsd has also been derived. A reaction mechanism is proposed to involve one pre-equilibria.First we select a Pt(IV) model drugs Na₂PtCl₆ to oxidate L- cysteine and L- cysteine hydrochloride, and study the kinetics of the reaction. Then we use HPLC to analyse Plant incretion GA₃ and IAA which distilled in the bacteria, were studied by HPLC and a new method to analyse plant incretion in the bacteria was build.Chapter one: The development of platinum anticacergrugs since 1965 and the development of analyse plant incretion by HPLC were reviewed in this chapter.Chapter two: The kinetics and mechanism of oxidation of L- cysteine hydrochloride by Na₂PtCl₆ has been studied by convertional spectrophotometry in this chapter.Chapter three: The plant incretion GA₃ and IAA which distilled in the bacteria, has been studied by HPLC and one new method to analyse plant incretion in the bacteria has been build.Chapter four: Conclusion and expectation are reviewed.