| A review has been accomplished for pharmacology about amygdalin and method of extracting it and the theory on supercritical extraction techniques, reverse micelle techniques and reverse micelle in supercritical carbon dioxide (SC-CO2). Surfactants soluble in SC-CO2, research methods and application technologies of reverse micelle in SCCO2 have also been summarized.Amygdalin was attained by the procedures of enzyme destroy, degreasing, extraction and recrystallization. And the effects of different solvent on the degreasing and the ethanol of different purity on the recrystallization were investigated. The optimized condition was got as follow: after degreasing by petroleum ether in 70-80℃ pool, Apricot-kernel was extracted by alcohol for three times and the crude Amygdalin was recystallized by alcohol for three times. The product with the purity 98% was obtained and the total retrieve rate is 34%.A variable-volume high pressure view cell apparatus has been designed and built for measuring cloud points by visul observation, which can operate at temperature and pressure under 333.15K and 40MPa. The equilibrium solubilities of two dodecylpolyoxyethylene polyoxypropylene ether nonionic surfactants (A(E0)m(PO)n) in supercritical carbon dioxide were measured at temperatures ranging from (308 to 328) K and pressures from (13.6 to 32.0) MPa. The experimental data were correlated using a semiempirical model. The calculated results show satisfactory agreement with the experimental data. The values of AARD are in the range (5 to 30) %.A variable-volume high-pressure extracting cell apparatus has been designed and built for measuring solubilization of amygdalin in PFPE/Water/CO2 system. According to the results, we found that the solubilization values increased with the increase of equilibrium time, size and amount of reverse micelles in supercritical carbon dioxide.
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