The Study Of Synthesis And Molecular Recognition Of Calix[4]pyrrole

The study of supramolecular chemistry is one of the most significant topics recently in the field of chemistry and biochemistry. It is the study of the non-covalent bond interaction between host molecules, such as cyclodextrins, crown ethers , calixarenes, and guest molecules. Molecular recognition, the process of that host molecule form binding with guest molecule selectively and product some special function, is one of the most important fields of the study on supramolecular chemistry. Molecular recognitions is not only information handling base for molecular-packages but also necessary pass for packing top-grade structure.Neutral molecular recognition, especially for neutral micromolecular, such as lower alcohol, simple amid- molecular, is one of the difficult questions in the study of supramolecular chemistry. Neutral micromolecular is difficult to form the strong non-covalent bond interaction with receptor molecular because of few locus of forming hydrogen-bonded action and lack of contact surface of forming hydrophobic action and π-π stacking action. Fortunately, calix pyrrole molecular have preferable recognition action to neutral micromolecular, and could achieve the separation of neutral molecular mixtures from application. So, studies on the calix pyrrole have gradually shown its potencial value and applicable prospect.In this thesis, synthesis conditions of aroma-substituted calix[4] pyrrole and calix[4]pyrrole derivatives are disscussed. The major synthetic compounds are as follows: meso-tetramethyl-meso-tetraphenyl calix[4]pyrrole, meso-tetraethyl-meso-tetra phenyl calix[4] pyrrole, meso -tetramethyl-meso-tetra (p-chlorophenyl) calix[4]pyrrole, meso-tetra-methyl-meso-tetra(p-bromophenyl)calix[4]pyrrole, meso-tetra methyl-meso-tetra(p-methoxyphenyl) calix[4]pyrrole, meso-tetra(p-cyclo pentyl-...