Research On The Size Modulation And Stabilization Effect Of Vitamin C And Amino Acid To The Selenium Nanoparticles In Aqueous Solution

The size modulation and stabilization effect of Vitamin C (Vc)and amino acid to the selenium nanoparticles (Nano Se⁰)in aqueous solution has been studied with the Transmission electron microscope (TEM),laser scattering (LS),Resonance Rayleigh Scattering (RRS),ultraviolet and visible spectrum (UV-VIS) and infrared spectrum(IR).1.The size modulation and stabilization effect of Vitamin C(Vc)The size modulation and stabilization effect of Vitamin C(Vc) has been studied, and the Vc-Nano Se⁰ was prepared. The LS results showed that when the Vc≤4mmol·L^-1, the mean diameter of the Nano Se⁰ was more than 300nm, and the range of the Nano Se⁰ was large; when the Vc≥0.05mol·L^-1, the mean diameter of the Nano Se⁰ was less than 100nm; and the range of the Nano Se⁰ was narrow. The TEM results showed the shape of Nano Se⁰ was familiar with ball. The RRS results showed that the Vc has good stabilization effect to the Nano Se⁰. The IR spectrum showed there were new absorb peaks appeared which predicated the contract between Vc and the Nano Se⁰.2. The size modulation and stabilization effect of single amino acid(Ami)The size modulation and stabilization effect of 6 single amino acid (Glycine, Lyscine, Proline,Methionine,Serine,Arginine) has been studied,and 6 Ami-Nano Se⁰ were prepared. The LS results showed that they all have the size modulation and stabilization ability to the Nano Se⁰, and their ability are different with each other. The Gly- Nano Se⁰ was steady in 40 days. The TEM results showed the shape of Nano Se⁰ was familiar with ball. The RRS results showed that the single amino acid have good stabilization effect to the Nano Se⁰. The IR spectrum showed there were new absorb peaks appeared which predicated the contract between single amino acid and the Nano Se⁰. 3.The size modulation and stabilization effect of mixed amino acid(Amis)The size modulation and stabilization effect of 2 Amis (Lyscine + Arginine, Serine + Histidine) have been studied. The LS results showed that they all have the size modulation and stabilization ability to the Nano Se⁰, and different with each other. The TEM results showed the shape of Nano Se⁰ was familiar with ball. The IR spectrum showed there were new absorb peaks appeared which predicated the contract between Amis and the Nano Se⁰.