Study On The Synthesis And Addition Reaction Of Phosphorus Acetylenic Compounds

Phosphine ligands especially chiral phosphine ligands have the remarkable significance both in fundamental research and practical applications in the asymmetric catalysis and host-guest inclusion-resolution chemistry fields. It's one of the hot points in chemistry and relative subject areas. In this dissertation we carried out the study on synthesis, additional reactivity and inclusion properties of new phosphorus acetylenic compounds, in order to find good host compounds that can form crystal super molecular system easily and a type of ligand for homogeneous transition metal catalyst.The precursor of chiral phosphine ligands, Bis (diphenylphosphinyl oxide) butadiyne (BDPPOB) was synthesized successfully, we optimized the synthesis route. The yield of BDPPOB was high, and the reaction manipulations were more convenient. The inclusion capacity of BDPPOB as host compound with kinds of organic small molecules was determined, and the theory of inclusion was analyzed. Four isomers were got through Diels-Alder addition reaction with BDPPOB and methylcyclopentadine. The structures of isomers were affirmed by IR, 1HNMR, MS and element analysis. Crystals of two isomers were obtained and their structures were determined by X-ray diffraction. The synthesis of chiral phosphine ligand phenylarylphosphine acetylene was investigated.The BDPPOB was a high selective host compound. The framework of the four double additional adducts were twisted and therefore suitable to be used as the precursors of chiral phosphine ligands. The both crystal structure 1 and 3 can prove that they have the inclusion capacity with solvent. Through the study of synthesis of phenylarylphosphine acetylene we open a new window for the investigation of chiral phosphine acetylene compounds.