Synthesis And Application Study Of The Aromatic Carboxylic Acid And Their Deiratives Complexes

With modern testing and analytical technology, the continuing development and synthesis of quantum mechanics technology, Coordination chemistry has developed rapidly, has become a chemistry, physics, materials, biology, information science and other academic research focus. It is not only organic chemistry, chemistry, physics, chemistry, biochemistry and structural chemistry, polymer chemistry, chemical industry, catalytic chemistry, the basis of mutual penetration of cross-cutting disciplines, but also materials science, life science and medicine and other disciplines interrelated form rich vitality of many new interdisciplinary, Such as bio-inorganic chemistry, organometallic chemistry.A series of coordination compounds have been synthesized through the carboxylic acid of small organic molecules as the raw material, and characterized the structure and researched into their character and application in this paper. The major results are:1,A 3D-supramolecular Framework compelx [Cu3(BTC)2(H2O)12]n where BTC is 1,3,5-Benzenetricarboxylic acid, has been synthesized and characterized by elemental analysis and single-crystal X-ray. We have studied the methylene blue, naphthol green B degradation process by microwave catalytic oxidation to [Cu3(BTC)2(H2O)12]n as the catalyst. The decomposition rate of the methylene blue, naphthol green B was dependent upon the initial concentration of the methylene blue, naphthol green B, the initial pH value of medium, and amount of catalys,reaction time the input power of microwave. The results showed that under optimum conditions of methylene blue (naphthol green B) degradation rate of more than 98%; By titration with a capacity of indirect determination of CO2 in the formation, degradation of methylene blue (naphthol green B) mineralization rate can reach above 70%; high performance liquid chromatography to ion-ion was found in solution exist SO42-, NO3-, halogen ions such as inorganic ions, achieve the purpose of completely inorganic, no secondary pollution. 2,A novel complex Ni[phen(DTC)2H2O]·0.5H2O where phen is 1,10-phena-nthroline and DTC was phthalic acid, was synthesized and characterized by IR spectra, elemental analysis and single-crystal X-ray. The crystal is orthorhombic, space group Pbcm with unit cell parameters:a=11.6669(6)A, b=11.1701(6)A, c=14.0370(6)A,α=90°,β=90°,γ=90°, V=1829.31(16)A3, Z=4, Mr=430.05, Dc=1.561Mg/cm3,μ=1.099mm-1, F(000)=884, T=293(2)K, R=0.0351, wR=0.0930 for 2160 reflections with I>2σ(Ⅰ). The crystal structure analysis shows that the nickel(Ⅱ) is a five-coordinated in a slightly distorted tetragonal pyramid.3,Designed and synthesized a new Schiff base ligand N1',N3',N5'-bis((pyridin-2-yl) amidine)benzene-1,3,5-tricarboxylimidic acid and, its copper complex CuL3, the use of IR spectra and elemental analysis, and 1H-NMR spectrum for characterization of its structure. At the same time, the interaction of the Schiff base L3 and its copper complex CuL3 with DNA was studied by fluorescence. The results of the experi-ment indicated that the Schiff base L3 and its copper complexes CuL3 with DNA model is the role of plug-in mode. Ethidium bromide(EB)was used as a probe, Obtained L3, CuL3 and DNA binding constants were k=1.8×105L/mol,2.3×105 L/mol, linear correlation were r=0.9409,r=0.9487. And we also studied that the ionic strength and different concentrations of [Fe(CN)6]4- impact on the fluorescence spectra of the the Schiff base L3 and its copper complex CuL3 with DNA system, the conclusion keep in line with the front.4,The mechanism of interaction between the Schiff base L3 and its copper complexes CuL3 and bovine serum albumin(BSA) was investigated with fluorescence spectrum-etry. The experiments showed that the selected the Schiff base L3 and its copper complexes CuL3 strongly quenched the fluorescence of protein, and this fluorescence quenching could be interpreted in terms of statistic quenching. And we have drawn the fluorescence quenching of BSA curve with L3 and CuL3 at different temperatures; and obtained fluorescence quenching constant and the binding constant number of binding sites. The interaction between L3 and CuL3 with protein was attributed to hydrophobic effect which was also confirmed by the calculation results of enthalpy and entropy for these reactions. Lastly, the effect of L3 and CuL3 on the conformation of BSA was further analyzed by synchronous fluorescence spectrometry and three-dimensional fluorescence spectra.