Spirolactam Ring-opening System Of Rhodamine Utilized As Fluorescence-enhanced Sensor For Heavy Metal Ions

In the production of life, heavy metal materials, widely used environmental problems caused by more and more cause for concern. For example:Pd2+ which deposited in the soil and plants near highways can pollut water.Pd2+ can harm human health effects with Thiol containing amino acid, protein (casein, silk protein and some enzymes), DNA and other biological macromolecules (vitamin B6). Cu2+ can participate in enzymatic reactions in vivo, and some redox enzyme transcription process, if the body of Cu2+ metabolism is not normal, it may induce a disease that occurs when the body Cu2+ content is too high, the toxic effect will be huge. Iron is an essential trace element for human body, also is the component of hemoglobin, myoglobin, heme enzyme. When the body lack of iron or iron overdose may occurs a series of symptoms. Therefore, the detection of heavy metals is of great significance.Compared with tranditional methods for the detection of metal ions, the fluorescent probes have afforded essential basis in the chemical and the biological systems for its many inherent merits including high specifity and high sensitivity. The spirolactam-ring opening system of rhodamine derivative would provide an excellent platform for the design and synthesis of fluorescence-enhanced sensor.Based on the spirolactam-ring opening system of rhodamine, we design and synthesize rhodamine derivatives with different ligane, RPd5, RCul and RFel, which is used as chemosensor for Pd2+, Cu2+ and Fe3+ respectively. The rhodamnine fluorescent Pd2+ probe RPd5 can detect Pd2+ in pool water and soil solution in proof-of-concept. The fluorescent probe RCul can detect Cu2+ with 1000-fold fluorescent enhancement. The fluorescence-enhanced sensor RFel for Fe3+ can display colorimetric methods specific for Cu2+...