Effects Of Daidzein On Muscule Growth,The Level Of Endocrinous And Cellular Immune Function In Male Rats

The effects of daidzein on muscle growth,the level of endocriones and cellular immune function in male rats were studied in this thesis.The presetent research includes three parts,and the result are shown as follows:1. Effects of Daidzein on Rats Growth and Muscle Growth in male RatsTwenty-four growing male rats were allotted randomely into three groups.The first growp(I group) was inspired daidzein of 50mg/kg body weight day for 30 days,the second group (II group) was inspired daidzein of 100mg/kg body weight dayfor 30 days,the control group(III group) was inspired peanut grease for 30 days.Compared to those of control group. The first growp increased body weight gain by 7.17%, gastrocsemins musle/body weight decreased by 0.4%, diameter of cell of muscle of gastrocsemins muscle increased 14.49%(p<0.05), density of cell of muscle increased 1.21%, diameter of lipocyte decreased 8.78%, density of lipocyte increased 5.45%, the differences were indistinctly; diameter of cell of cardial muscle increased 23.31% (p<0.01), density of cell of cardial muccule increased 2.1%, diameter of cardial lipocyte decreased 8.91%, density of cardial lipocyte have no change.The second growp decreased body weight gain by 5.86%, gastrocsemins muscle/body weight decreased by 0.05%, diameter of cell of musle of gastrocsemins musle decreased 10.74%, density of cell of musle increased 2.43%, diameter of lipocyte decreased 4.88%, density of lipocyte decreased 3.64%; diameter of cell of cardial muccule decreased4.14%, density of cell of cardial muscle increased 1.1%; diameter of lipocyte decreased 6.5%, density of lipocyte decreased 1.76%,the differrences were indistinctly.2. The Level of Endocrinous in Male RatsCompared to those of control group, The first growp's blood concentration of testosterone and GH were elevated by 23.89% (p<0.05) and 15.07% (p<0.05) .The second growp's blood concentration of testosterone and GH were decreased by 51.25% (p<0.01) and 13.38% (p<0.05) .3. Effects of Daidzein on Cellular Immune Function in Male RatsThe first group thymus gland/weight increased by 16.88% (p<0.01) ,the Red Blood Count(RBC) and the White Blood Count (WBC) and the trend of ANNE positive rate of lymphocytes increased by 33.19% (p<0.05), 18.18% (p>.05),and 15.86% (p<0.05)0 Compared to those of control group, The second gthymus gland/weight increased by 25.65% (pO.Ol) ,the Red Blood Count(RBC) and the White Blood Count (WBC) and the trend of ANNE positive rate of lymphocytes decreased by 3.63% (p>0.05) , 3.1 % (p>0.05) ,and6.3% (p>0.05)0 These experiment indicate that low dosage of daidzein can promote the growth of rats and cellular immune function by increase the levels of endocrines hormone,white high dosage of daidzein can inhibit it.In conclusion, 50mg/kg Daidzein can improve the level of endocrines ,growth of muscle ,Cellular Immune Function in Male Rats.But the 100mg/kg Daidzein have the reverse effect...