Epidemiologic Investigation And Inactivated Vaccine Of Yellow Scour And White Scour Of Newborn Piglets In TongLiao Area Of Inner Mongolia

1 to 30 days old piglet were selected from 12 scale farms and 23 farmers in 7 countries in TongLiao area to investigate of the incidence and mortality rate of yellow scour and white scour of new born piglet. The result showed that this disease had a relatively epidemic scope and high incidence and mortality rate every year. The incidence and mortality rate of yellow scour and white scour of new piglets could be decreased by early iron suppling and food breeding ,well sanitization before and periodically sanitization after the sow delivery.158 strains of Escherichia. coli were identificated by morphological and biochemistry character in 216 sam;les of suspicious yellow scour and white scour of piglets collected from 12 scale farms and 23farmers. In the 158 strains ,134 isolates could be indentificated serotype with monovalence anti-0 antigen antibodies of E.coli which belonged to 6 serotypes. Theywere O₁49,O₆0,O₉,O₁41,O₂0 and O₈.14 kinds of antibiotics were used in the antibiotic resistence test to the 158 isolates of panthogenic E.coli and the reference strain of E.coli ATCC25922. The most sensitive antibiotic was an the second one was , the other were in turngentamycin, chloramphenicol, norfloxacin, neomycin, kanamycin et al. The tested strains showed different degree of resitence to antibiotics, and there were 7 strains show resistence to 10 kinds ofantibiotics, 158 strains show resistence to 14 antibiotics.Six E.coli strains isolated from 158 with yellow scour and white scour of newborn piglets were selected as the vaccine strains. The inactivated vaccine was made and immunized the pregnant sows in the farm, and the K88k99 genetic engineering vaccine and saline were as control. The result were that the incidence rate of different group immuned with inactivated vaccine,the K88K99 and asline were in turn 9.48%, 29.37% and 36.57% respectively, and the mortality rate were 2.18%, 16.67% and 28.36% repectively. It could be concluted that the E.coli inactivated vaccine had a efficient immune effect.