Application Of Mitomycin C In The Treatment Of Nasolacrimal Duct Obstruction With High Frequency Jun Tong Combined Stent Implantation

Objective：To discuss the therapeutic effect of motomycin-C and high-frequencyelectrolacryocrystoplasty combining with lacrimal drainage tube implantation in thetreatment of naso-lacrimal duct0bstruction.Methods,67cases(81eyes)with naso-lacrimal duct obstruction were randomlydivided into two groups treatment group and control group In treatment group，34cases(41eyes)were accepted high-frequency electrolacryocrystoplasty，and1m Imitomycin-C0.4mg／ml was injected into lacrimal duct for five minutes then washedwith09％NS quickly and putted lacrimal drainage tube trough the new lacrimalpassage Lacrimal drainage tubes were removed after3months Control group of33cases(40eyes)were done the same operate，but were not injected.mitomycin-C It was regularly flushed the lacrimal passage aF(er removed tubesFollowing up6months，the therapeutic effects were compared among the groupsResults：Following up3months，in treatment group of34cases(41eyes)，systems were completely resolved in37eyes，and the cure rate was927％：Incontrol group of33cases(40eyes)，70％of cases were recovered Follow up6months The cure rate of treatment group was902％but65％of control groupwere recovered The cure rate in treatment group was higher than that in controlgroup The difference between two groups was significant(p<O05).Conclusion l high-frequency electrolacryocrystoplasty combining with lacrimaldrainage tube implantation is a safe and an effective technique for naso-lacrimalduct obstruction，because of its less invasive nature and complications It mayserve as an alterative method for the treatment of naso-lacrimal du cl Obstruction ltcan remarkably improve the cure rate applying mitomycin-C during surgery Thismethod of surgery should be generalized in clinic.