| Objective:Through the detection of Liu wei di huang pill on rabbit nucleus pul posus cells apoptosis in degeneration, To explore the effect of Liuwei di huang pill caused by discogenic low back pain which caused by intervertebral disc deg eneration. To make Tonifying Kidney method intervention disc nucleus pulposus cells apoptosis become a new therapeutic targets. Offers a new treatment for int ervertebral disc degenerative diseases related diseases.Method:80New Zealand white rabbits were randomly divided into Liu wei di huang pill group, model group, control group and normal control group four gr oups. Model group, Liu wei di huang pill group to establish animal model of i ntervertebral disc degeneration. Liu wei di huang pill group to the suspension li quid lavage Liu wei di huang pill. More than threegroups with the same physio logical saline lavage. kill animals in2,4,6,8weeks in batches. Return disc sa mples.Result:Apoptosis rate of Liu wei di huang pill group and model group were hi gher than control group and normal control group. The differenceis statistically significant (P<0.05). Illustrate the rabbit model of degenerative intervertebral disc has been established. Groups of nucleus pulposus cells apopto sis rate as the extension of feeding time. Rose less blankgroup and control grou p. The apoptosis rate of no significant differencebefore and after the experiment (P>0.05). While the rise in model group and the group of Liu wei di huang pill is more. Within the group to compare difference is statistically significant (P <0.05). And the apoptosis rate of Liu wei di huang pill group rose less than model group. Liu wei di huang pill can ease the nucleus pulposus cell apoptosi s rate. Each time point set of Liu wei di huang pill apoptosis rate apoptosis rat e in the model group differences were statistically significant.(P<0.05). That partLiu wei di huang pill can delay the nucleus pulposus cells apoptosis.
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