| Citrus aurantium is commonly used traditional Chinese medicine of regulating the qi,the first recorded in "Shen Nong’s Herbal Classic",it’s listed as middle products,which commonly used in the treatment of spleen and stomach,abdominal pain,bloating. The current lack of research on the chemical composition of citrus aurantium efficacy.In order to get the constituents of citrus aurantium herbs pharmacodynamic data to carry out the development and production of Chinese Herbs,this subject of some research on citrus aurantium.This issue through the extraction of separation and purification of citrus aurantium herbs,total flavonoids and total alkaloid substances, both pharmacodynamic study and compare. The selection process of L9(34)orthogonal design table of preferred water extract citrus aurantium herbs, crude extracts of herbs. The polyamide resin on the crude extracts were separated and purified by single factor to determine the best kind of liquidon the sample liquid flow rate, adsorption time and elution solvent type and amount ofelution solvent, the final content of6.823%of the total alkaloid extract dried paste andcontent of88.63%of total flavonoid substances dry paste. The total alkaloid substanceafter further purification content of43.5%of the residues and59.02%of dry extract.Composition characterization of the extract obtained by HPLC, total flavonoids containnaringin, neohesperidin, it also contains the rue naringin, hesperidin, orange peel, prime,naringenin, nobiletin and other factors total alkaloid extract contains synephrine. The pharmacodynamics of the two types of substances, the establishment of appropriate animal models to observe the impact of the extract on peristalsis and gastric emptying inmice, and compared, initially identified from the broken gas consumption in the Citrus aurantium plot dredge stasis pharmacodynamics of pharmacological compounds. Providesresearch ideas and experimental basis for the allegations of citrus aurantium herbs and drug discovery.
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