Effect Of Yiqi Warming Sun Drugs On NF - KBp65 In Patients With Allergic Rhinitis

Objective:This topic through Yiqiwenyang drug therapy in patients with lung deficiency type allergic rhinitis, the symptoms observed in patients before and after treatment, to determine the clinical efficacy of the drug Yiqiwenyang allergic rhinitis patients; and to detect patients before and after treatment in nasal mucosa NF-kBp65 expression to explore Yiqiwenyang party in the treatment of allergic rhinitis, and whether inhibition of NF-kB p65 expression, reducing it to the inflammatory cytokine gene expression, thereby reducing the symptoms of allergic rhinitis.Method:All patients were from Sichuan Province, West China Hospital of Sichuan University Hospital and Department of Otolaryngology clinics and wards, according to the inclusion criteria were screened, sixty patients with standard-compliant patients. Using parallel group design, the treatment group thirty cases, thirty cases in the placebo group, and the other to select eight healthy subjects for the control group. The treatment group experienced instructors square "photo tears congested nose side only" smart free fried particle therapy, the placebo group was given the same free fried outer particles, a course of four weeks, health groups do not take any drugs. Observe and record the patient’s symptoms during treatment, the signs and symptoms and integral changes, and compared between the two groups before and after treatment and groups. Under turbinate mucosa were taken before and after treatment in patients, the use of immunohistochemistry to detect the expression of inferior turbinate mucosa of NF-kBp65.Results:Completion:A total of seventy patients met the diagnostic criteria, complete the sixty cases in which the treatment group and the placebo group (thirty cases); signs and symptoms before and after treatment compared to seventy cases markedly effective in ten cases, three cases, total efficiency of ninety percent. In addition to spontaneous and disease areas, Yaoxisuanruan or urine long effect is not significant, the other symptoms were significantly improved. After the placebo treatment, zero cases markedly effective in six cases, twenty-four cases, the total efficiency of twenty percent, the two groups in terms of symptoms and signs and symptoms and were significantly different (P<0.05). Before the nasal mucosa were positive expression of NF-kBp65 treated patients, and was significantly higher. After medicine treatment significantly decreased the expression of their nasal mucosa NF-kB p65 protein.Conclusion:Taking SheTiZhiQiu prescription to treat the lung and kidney deficiency symptoms of allergic rhinitis are all valid, can significantly improve the symptoms of nasal symptoms and yang; and with the course of the increase, the total effective rate is gradually increased, which indicates that the Yiqiwenyang medicine is an effective method of Chinese medicine treatment of allergic rhinitis.