| This Research studied the effect of active dry yeast and Se-enriched yeast on sows performance and immune response. Single factor design was adopted and 12 Yorkshire sows, which were littermate or semi-littermate with similar body weight(initially 250 Kg of mean body weight) at the similar gestation day(86 day), were randomly allotted to 3 treatments (active dry yeast, Se-enriched yeast, control), there were four replicates with one sow per replicate in one treatment. The diet was corn-soy bean meal, during late gestation, the sows in each treatment were fed the assigned amount of experimental diet. during lactation, all sows were allowed ad libitum access to lactational diet. Reproductive performance of sows (number of pigs/littler at birth, number of live pigs/littler at birth, number of pigs/littler at weaning, total littler weight at birth, total littler weight at weaning), production performance of piglets (food intake, daily gain and diarrhea) were recorded.Results showed active dry yeast and Se-enriched yeast improved number live pigs/littler at birth of sows fed active dry yeast or Se-enriched yeast by 22.86%, 11.42%, respectively. Piglets birth weight was improved by 18.03%(p<0.05) and 19.02%, respectively. Compared with the control, total littler weight at weaning and mean weaning body weight of sows fed active dry yeast significantly increased by 16.32%(p<0.05) and 15.42%(p<0.05) respectively, and ADG of piglets increased by 7.1%. Diarrhea index of sows fed Se-enriched yeast and active dry yeast were decreased by 68.88% and 39.74%. Compared with the control, blood serum IgA of sows which fed Se-enriched yeast was enhanced by 43.59%, and blood serum IgA of piglets was significantly enhanced by 22.53%(p<0.05).Se-enriched yeast can significantly increase sow milk selenium, sow blood plasma selenium concentration and piglets blood plasma selenium concentration (P<0.05 ) . Compared with the control, milk selenium, colostrums selenium, milk selenium, sow blood...
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