| OBJECTIY Pituitary adenoma is an common intra-cranial tumor, about 10 percent of intra-cranical tumors.The detecting the change of pituitary hormone after tumor excision aims to make groups of pituitary adenoma before operation and to detect the postopera-tional pituitary as well as to suit an effective method to decide the degrees of tumor removal and reoccour after operation.METHODS Among 50 patients with pituitary hormone, the analysis of the value of pituitary hormone is reviewed retrospectively, according to the degree of tumor removal . The values of pituitary hormone on each group between preoperation and postoperation are analysed by t-test of paired samples. The values of postoperation pituitary hormone between two groups are analysed by t-test of mean of two samples. The clinical significant of relationship between the degree of tumor removal and the values of pituitary hormone is di scovered.RESULTS The values of pituitary hormone after operation are decrease significantly after both complete and uncomplete tumor removal in PRL adenomas as well as GH adenomas (P<0. 05) , which shows operationscan correct the disturbance of endocrine. After comparing the values of pituitary hormone between the complete group and the uncomplete group, there is significant difference which shows the degrees of tumor removal affect the values of pituitary hormone after operation (P<0.05).CONCLUSION The higher level of pituitary hormone can be cut down by operat ion,which demonstrates operation can' t be rep 1 ac ed. "In1 dei;reeof tumor removal plays an role in the change o em ocrine, which shows pituitary adenomas must be completely excised based on not injurying the normal pituitary tissues.PURPOSE There is correlation between the degree of tumor removal and the correction of endocrine. The detection of endocrine hormone can he used to evalue the effciacy of operation,which plays an important role in clinical treatment of pituitary adenomas ami prognosis.
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