Study On The Chemical Constituents Of Bidens Bipinnata

Bidens bipinnata,a weed of the compositae family,is widely distributed in China,and has been used as a traditional Chinese folk medicine for a long time.Studies of the biological activities show that Bidens bipinnata has anti-inflammatory activity ,antimicrobial activity,cardiovascular activity and antileukemia activity.Polyacetylenes and flavones are the main active chemical constituents of Bidens bipinnata.Little work has been done to study the polyacetylenes constituents of Bidens bipinnata,and its flavones constituents also need studying.In this chemical study on Bidens bipinnata,after repeating silica gel,reversed phase silica gel column chromatography and polyamide column chromatography,we obtained ten compounds,and identified six compounds'structures.The six compounds are: trideca-2-p-D-glucopyranosyl-1,13-dihydroxy-3(E),11(E)-di en-5,7,9-triyne(l), trideca-2-p-D-glucopyranosyl-l,13-dihydroxy-11(E)-dien -3,5,7,9-tetrayne(2),Hyperoside(3),6-O-(3",6"-diacetyl-p-D-glucopyranosyl)-6,7,3',4'-tetrahydroxyaurone(4),6-O-(6"-acetyl-p-D-glucopyranosyl)6,7,3',4' -tetrahydroxyaurone(S), 6-O-(4",6"-diacetyI-p-D-glucopyranosyl)6,7,3',4'-te tr'ahydroxyaurone(6) .Compound2 and compound4 are two new compounds,compound5 is first isolated from this plant.